Ovarian changes during pregnancy and pseudopregnancy in the vole, Microtus agrestis

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dc.contributor.authorBreed, W.G.
dc.contributor.authorClarke, J.R.
dc.date.issued1970
dc.description.abstractIn the vole, Microtus agrestis, there was no significant change in the number of corpora lutea (cl) during either pregnancy or pseudopregnancy. In pregnant animals, two waves of luteal development took place and histological changes during the two phases of growth differed. In pseudopregnant animals, a similar increase occurred initially which was followed by a marked decrease after Day 8, at which time cl began to degenerate. Luteinized follicles were visible early in pregnancy and pseudopregnancy. Graafian follicles were present after Day 2 or 3. In pregnant animals, the number remained more or less constant, except for a slight increase on Day 19, but their maximum size was reduced at about mid-term, whereas, in pseudopregnant animals, a marked increase in size occurred between Days 8 and 10. Vaginal smears and histology indicated progesterone secretion up to Day 19 of pregnancy and for the 8 to 9 days of pseudopregnancy. There was, therefore, a good correlation between the presence of healthy cl and smears that indicated progesterone secretion.
dc.description.statementofresponsibilityW. G. Breed and J. R. Clarke
dc.identifier.citationReproduction, 1970; 23(3):447-456
dc.identifier.doi10.1530/jrf.0.0230447
dc.identifier.issn0022-4251
dc.identifier.issn1741-7899
dc.identifier.orcidBreed, W.G. [0000-0003-1739-6593]
dc.identifier.urihttp://hdl.handle.net/2440/91448
dc.language.isoen
dc.publisherSociety for Reproduction and Fertility
dc.rightsCopyright status unknown
dc.source.urihttps://doi.org/10.1530/jrf.0.0230447
dc.subjectOvary
dc.subjectCorpus Luteum
dc.subjectOvarian Follicle
dc.subjectUterus
dc.subjectVagina
dc.subjectEpithelium
dc.subjectLeukocytes
dc.subjectEosinophils
dc.subjectAnimals
dc.subjectRodentia
dc.subjectProgesterone
dc.subjectEstrogens
dc.subjectVaginal Smears
dc.subjectPregnancy
dc.subjectPregnancy, Animal
dc.subjectPseudopregnancy
dc.subjectFemale
dc.titleOvarian changes during pregnancy and pseudopregnancy in the vole, Microtus agrestis
dc.typeJournal article
pubs.publication-statusPublished

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