Insulin-like growth factor-I (IGF-I) : role and application in intestinal disease / Gordon Stanley Howarth.
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Date
2001
Authors
Howarth, Gordon Stanley
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Thesis
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Abstract
Describes studies which extended the understanding of growth factors, particularly of IGF-I in gut growth and repair in addition to the physiological role and hence, therapeutic potential, of a range of growth factors in gastrointestinal disease. It is suggested that future evaluation of the application of growth factors to combat gastrointestinal disorders could focus on functional outcomes such as effects on intestinal absorption. In addition, the efficacy of growth factor analogues with increased bioactivity, possibly incorporated into enterally-administered growth factor formulations, either enriched in, or depleted of, certain specific growth factors, could be investigated as a novel treatment strategy for diseases of the gastrointestinal tract.
School/Discipline
Dept. of Physiology
Dissertation Note
Thesis (Ph.D.)--University of Adelaide, Dept. of Physiology, 2001
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This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exception. If you are the author of this thesis and do not wish it to be made publicly available or If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at: http://www.adelaide.edu.au/legals. Copyright material removed from digital thesis. See print copy in University of Adelaide Library for full text.
Description
"November 2001."
Author's previously published articles appended.
Bibliography: leaves 80-106.
xii, 139 leaves : ill, charts ; 30 cm.
Author's previously published articles appended.
Bibliography: leaves 80-106.
xii, 139 leaves : ill, charts ; 30 cm.