CRP Correlates with clinical score in ulcerative colitis but not in Crohn's disease

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dc.contributor.authorRodgers, A.
dc.contributor.authorCummins, A.
dc.date.issued2007
dc.descriptionThe original publication can be found at www.springerlink.com
dc.description.abstractThe aim of this study was to prospectively evaluate the correlation between clinical scoring systems and C-reactive protein (CRP) in inflammatory bowel disease. The modified Harvey-Bradshaw index was used in 40 patients (58 assessments) with Crohn’s disease, and the Lichtiger score in 29 patients (36 assessments) with ulcerative colitis. In ulcerative colitis, CRP was elevated in 14%, 42%, 64%, and 83%, respectively, of subjects with quiescent, mild, moderate, and severe disease. There was a linear correlation of log(CRP) with clinical score except for proctitis. In Crohn’s disease, CRP was elevated in 54%, 70%, 75%, and 100%, respectively, of subjects with quiescent, mild, moderate, and severe disease. We conclude that the clinical score has a good correlation with CRP in ulcerative colitis except for proctitis, whereas clinical score has a poor correlation with CRP in Crohn’s disease, particularly in those with clinically quiescent, fibrostenotic, and ileal disease.
dc.description.statementofresponsibilityAlexander D. Rodgers and Adrian G. Cummins
dc.description.urihttp://www.springer.com/medicine/internal/journal/10620
dc.identifier.citationDigestive Diseases and Sciences, 2007; 52(9):2063-2068
dc.identifier.doi10.1007/s10620-006-9691-2
dc.identifier.issn0163-2116
dc.identifier.issn1573-2568
dc.identifier.orcidCummins, A. [0000-0003-3115-9498]
dc.identifier.urihttp://hdl.handle.net/2440/44207
dc.language.isoen
dc.publisherKluwer Academic/Plenum Publ
dc.source.urihttps://doi.org/10.1007/s10620-006-9691-2
dc.subjectC-reactive protein
dc.subjectCrohn’s disease
dc.subjectErythrocyte sedimentation rate
dc.subjectInflammatory bowel disease
dc.subjectUlcerative colitis
dc.titleCRP Correlates with clinical score in ulcerative colitis but not in Crohn's disease
dc.typeJournal article
pubs.publication-statusPublished

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