Endocrinology of anorexia of ageing

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dc.contributor.authorChapman, I.
dc.date.issued2004
dc.description.abstractAppetite and food intake decrease with normal ageing, predisposing to the development of under-nutrition. Under-nutrition is common in older people and has been implicated in the development and progression of chronic diseases commonly affecting the elderly, as well as in increasing mortality. An understanding of the factors that contribute to the physiological and pathological declines in food intake in older people is likely to aid in the development of effective forms of prevention and treatment. Ageing affects many of the endocrine factors involved in the control of appetite and feeding but few studies have been performed in humans to clarify these changes. Possible hormonal causes of the anorexia of ageing include increased activity of cholecystokinin, leptin and various cytokines and reduced activity of ghrelin and testosterone.
dc.description.statementofresponsibilityIan McPhee Chapman
dc.identifier.citationBest Practice and Research: Clinical Endocrinology and Metabolism, 2004; 18(3):437-452
dc.identifier.doi10.1016/j.beem.2004.02.004
dc.identifier.issn1521-690X
dc.identifier.issn1532-1908
dc.identifier.urihttp://hdl.handle.net/2440/9288
dc.language.isoen
dc.publisherBailliere Tindall
dc.rights© 2004 Bailliere Tindall
dc.source.urihttps://doi.org/10.1016/j.beem.2004.02.004
dc.subjectsarcopaenia
dc.subjectcholecystokinin
dc.subjectanorexia
dc.subjectghrelin
dc.subjectleptin
dc.subjectcytokines
dc.subjecttestosterone
dc.subjectageing
dc.titleEndocrinology of anorexia of ageing
dc.typeJournal article
pubs.publication-statusPublished

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