Localization of the ring-infected erythrocyte surface antigen (RESA) of Plasmodium falciparum in merozoites and ring-infected erythrocytes

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dc.contributor.authorBrown, G.V.
dc.contributor.authorCulvenor, J.G.
dc.contributor.authorCrewther, P.E.
dc.contributor.authorBianco, A.E.
dc.contributor.authorCoppel, R.L.
dc.contributor.authorSaint, R.B.
dc.contributor.authorStahl, H.D.
dc.contributor.authorKemp, D.J.
dc.contributor.authorAnders, R.F.
dc.date.issued1985
dc.description.abstractImmunoelectron microscopy with protein A gold has been used to determine the subcellular location of the ring-infected erythrocyte surface antigen (RESA) of Plasmodium falciparum. RESA was associated with dense vesicles presumed to be micronemes within merozoites. RESA was not detected on the surface of merozoites but was located at the membrane of erythrocytes infected with ring-stage parasites. RESA within merozoites was largely soluble in the nonionic detergent Triton X-100, but was insoluble in this detergent when associated with the erythrocyte membrane.
dc.description.statementofresponsibilityG V Brown, J G Culvenor, P E Crewther, A E Bianco, R L Coppel, R B Saint, H D Stahl, D J Kemp, and R F Anders
dc.identifier.citationJournal of Experimental Medicine, 1985; 162(2):774-779
dc.identifier.doi10.1084/jem.162.2.774
dc.identifier.issn0022-1007
dc.identifier.issn1540-9538
dc.identifier.urihttp://hdl.handle.net/2440/85869
dc.language.isoen
dc.publisherRockefeller University Press
dc.rights© 1985 Rockefeller University Press
dc.source.urihttps://doi.org/10.1084/jem.162.2.774
dc.subjectErythrocytes
dc.subjectAnimals
dc.subjectHumans
dc.subjectPlasmodium falciparum
dc.subjectMalaria
dc.subjectAntigens, Protozoan
dc.subjectAntigens, Surface
dc.subjectMicroscopy, Electron
dc.titleLocalization of the ring-infected erythrocyte surface antigen (RESA) of Plasmodium falciparum in merozoites and ring-infected erythrocytes
dc.typeJournal article
pubs.publication-statusPublished

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