Magnesium and traumatic brain injury

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dc.contributor.authorTurner, R.
dc.contributor.authorVink, R.
dc.contributor.editorWilson, R.
dc.contributor.editorPreedy, V.
dc.contributor.editorZibadi, S.
dc.date.issued2013
dc.description.abstractMagnesium is one of the most important ions in the body and is present in high concentrations within all cells. It is indispensable in terms of maintenance and regulation of general cellular metabolism and function due to the central roles it plays in nearly every aspect of cell function, including energy metabolism and maintenance of ionic gradients. Given that magnesium is so essential for normal cellular function, disruption of magnesium homeostasis has deleterious consequences. Indeed, the detrimental effects of the disruption of magnesium homeostasis are clearly observed following trauma to the CNS, leading to serious biochemical changes. Accordingly, the aim of this chapter is to review both the role of magnesium in secondary injury following traumatic brain injury (TBI) and also the efficacy of the experimental and clinical administration of magnesium as a novel therapeutic for the treatment of TBI.
dc.description.statementofresponsibilityRenée J. Turner and Robert Vink
dc.identifier.citationMagnesium in Human Health and Disease, 2013 / Wilson, R., Preedy, V., Zibadi, S. (ed./s), pp.255-267
dc.identifier.doi10.1007/978-1-62703-044-1_18
dc.identifier.isbn9781627030434
dc.identifier.orcidTurner, R. [0000-0003-4278-8302]
dc.identifier.orcidVink, R. [0000-0002-4885-0667]
dc.identifier.urihttp://hdl.handle.net/2440/79151
dc.language.isoen
dc.publisherSpringer
dc.publisher.placeUnited States
dc.rights© 2013 Springer Science+Business Media New York
dc.source.urihttps://doi.org/10.1007/978-1-62703-044-1_18
dc.subjectTraumatic brain injury
dc.subjectMagnesium
dc.subjectSecondary injury
dc.subjectCentral nervous system
dc.titleMagnesium and traumatic brain injury
dc.typeBook chapter
pubs.publication-statusPublished

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