Lifestyle management improves quality of life and depression in overweight and obese women with polycystic ovary syndrome
dc.contributor.author | Thomson, R. | |
dc.contributor.author | Buckley, J. | |
dc.contributor.author | Lim, S. | |
dc.contributor.author | Noakes, M. | |
dc.contributor.author | Clifton, P. | |
dc.contributor.author | Norman, R. | |
dc.contributor.author | Brinkworth, G. | |
dc.date.issued | 2010 | |
dc.description.abstract | Objective: To assess the impact of adding exercise to dietary restriction on depressive symptoms and health-related quality of life (HRQOL) in women with polycystic ovary syndrome (PCOS). Design: Analysis of depression and quality of life outcomes from a randomized, controlled prospective clinical intervention that evaluated the effects on a range of health outcomes in women with PCOS. Setting: Clinical research unit. Patient(s): One hundred four overweight/obese PCOS women (aged 29.3 ± 0.7 years; body mass index [BMI] 36.1 ± 0.5 kg/m2). Intervention(s): Randomized to one of three 20-week lifestyle programs: diet only, diet and aerobic exercise, or diet and combined aerobic-resistance exercise. Main Outcome Measure(s): Depression and PCOS-specific HRQOL. Result(s): Forty-nine women completed the intervention (diet only = 14, diet and aerobic exercise = 15, diet and combined aerobic-resistance exercise = 20). By week 20 all groups achieved weight loss and had improvements in depression and PCOS-specific HRQOL scores, except for body hair domain score. There was no difference between treatments for all outcomes. Conclusion(s): This study demonstrated that dietary restriction alone and combined with exercise had similar benefits for improving depression and HRQOL scores in overweight and obese women with PCOS. | |
dc.description.statementofresponsibility | Rebecca L. Thomson, Jonathan D. Buckley, Siew S. Lim, Manny Noakes, Peter M. Clifton, Robert J. Norman and Grant D. Brinkworth | |
dc.identifier.citation | Fertility and Sterility, 2010; 94(5):1812-1819 | |
dc.identifier.doi | 10.1016/j.fertnstert.2009.11.001 | |
dc.identifier.issn | 0015-0282 | |
dc.identifier.issn | 1556-5653 | |
dc.identifier.orcid | Thomson, R. [0000-0002-7807-4144] | |
dc.identifier.orcid | Clifton, P. [0000-0002-6411-626X] | |
dc.identifier.orcid | Norman, R. [0000-0002-3118-3896] | |
dc.identifier.uri | http://hdl.handle.net/2440/57437 | |
dc.language.iso | en | |
dc.publisher | Elsevier Science Inc | |
dc.source.uri | https://doi.org/10.1016/j.fertnstert.2009.11.001 | |
dc.subject | Weight loss | |
dc.subject | exercise | |
dc.subject | diet | |
dc.subject | depression | |
dc.subject | quality of life | |
dc.title | Lifestyle management improves quality of life and depression in overweight and obese women with polycystic ovary syndrome | |
dc.type | Journal article | |
pubs.publication-status | Published |