Tissue oxygenation and red cell 2,3-diphosphoglycerate in normal and abnormal pregnancy

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dc.contributor.authorMacLennan, A.H.
dc.contributor.authorEmerson, P.M.
dc.contributor.authorHunter, D.J.S.
dc.contributor.authorDarley, J.H.
dc.date.issued1976
dc.descriptionArticle first published online: 23 AUG 2005
dc.description.abstractMaternal tissue oxygenation was reflected by the level of red cell, 2,3-diphosphoglycerate (DPG) was measured before, during and after normal pregnancy. Following an initial fall at the beginning of pregnancy there was a significant rise in the mean level of DPG during pregnancy with an abrupt fall in the puerperium. The mean red cell DPG level in the third trimester of pregnancies complicated by pre-eclampsia and diabetes was not statistically different from the normal but the mean value of all pregnancies in which the fetus was stillborn or growth retarded was significantly lower (p less than 0-001). The possible mechanism of the changes in normal and abnormal pregnancy is discussed and it is suggested that the measurement of red cell DPG in the third trimester of pregnancy may prove to be a useful parameter of placental oxygenation.
dc.description.statementofresponsibilityA. H. Maclennan, Pauline M. Emerson, D. J. S. Hunter and J. H. Darley
dc.identifier.citationBritish journal of obstetrics and gynaecology, 1976; 83(5):378-382
dc.identifier.doi10.1111/j.1471-0528.1976.tb00846.x
dc.identifier.issn0306-5456
dc.identifier.issn1471-0528
dc.identifier.urihttp://hdl.handle.net/2440/91450
dc.language.isoen
dc.publisherBlackwell Science
dc.rightsCopyright status unknown
dc.source.urihttps://doi.org/10.1111/j.1471-0528.1976.tb00846.x
dc.subjectErythrocytes
dc.subjectHumans
dc.subjectPregnancy Complications
dc.subjectFetal Death
dc.subjectPre-Eclampsia
dc.subjectPregnancy in Diabetics
dc.subjectDiphosphoglyceric Acids
dc.subjectOxygen Consumption
dc.subjectPregnancy
dc.subjectMaternal-Fetal Exchange
dc.subjectFemale
dc.titleTissue oxygenation and red cell 2,3-diphosphoglycerate in normal and abnormal pregnancy
dc.typeJournal article
pubs.publication-statusPublished

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