The interaction of phospholipid transfer protein with high density lipoproteins / Nongnuch Settasatian.

Date

2001

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Settasatian, Nongnuch

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Abstract

This thesis is concerned with the interaction of the plasma factor, phospholipid transfer protein (PLTP) with HDL. The studies described in this thesis define the mechanism of the remodelling of reconstitute HDL (rHDL) by PLTP and the reasons why triglyceride enrichment of rHDL enhances the remodelling process. Other studies describe why triglyceride enrichment of rHDL enhances PLTP-mediated phospholipid transfers. In conclusion, this thesis describes the mechanism of the PLTP-mediated remodelling of rHDL and presents reasons why the remodelling is enhanced in particles that are enriched with triglyceride.

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Dept. of Medicine

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Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 2001

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This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exception. If you are the author of this thesis and do not wish it to be made publicly available or If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at: http://www.adelaide.edu.au/legals

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Errata attached to inside front cover.
Bibliography: leaves 112-166.
xi, 166 leaves : ill. (some col.) ; 30 cm.

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