Unprecedented staining of polar lipids by a luminescent rhenium complex revealed by FTIR microspectroscopy in adipocytes

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2016

Authors

Bader, C.
Carter, E.
Safitri, A.
Simpson, P.
Wright, P.
Stagni, S.
Massi, M.
Lay, P.
Brooks, D.
Plush, S.

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Molecular Biosystems, 2016; 12(7):2064-2068

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C. A. Bader, E. A. Carter, A. Safitri, P. V. Simpson, P. Wright, S. Stagni, M. Massi, P. A. Lay, D. A. Brooksa and S. E. Plush

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Abstract

Fourier transform infrared (FTIR) microspectroscopy and confocal imaging have been used to demonstrate that the neutral rhenium(i) tricarbonyl 1,10-phenanthroline complex bound to 4-cyanophenyltetrazolate as the ancillary ligand is able to localise in regions with high concentrations of polar lipids such as phosphatidylethanolamine (PE), sphingomyelin, sphingosphine and lysophosphatidic acid (LPA) in mammalian adipocytes.

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Data source: Supplementary information, http://www.rsc.org/suppdata/c6/mb/c6mb00242k/c6mb00242k1.pdf

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This journal is © The Royal Society of Chemistry 2016. Open Access Article. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

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