New roles for old holes: Ion channel function in aquaporin-1

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2002

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Yool, A.
Weinstein, A.

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Journal article

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Physiology, 2002; 17(2):68-72

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Andrea J. Yool and Alan M. Weinstein

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Abstract

Mammalian aquaporins are part of the diverse major intrinsic protein family of water and solute channels. Intriguing links exist in structural and functional properties between aquaporins and ion channels. A novel role for aquaporin-1 as a gated ion channel reshapes our current views of this ancient family of transmembrane channel proteins.

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© 2002 Int. Union Physiol. Sci./Am. Physiol. Soc.

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