Probiotics and prebiotics as a therapeutic strategy for inflammatory bowel disease.

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09phg3121.pdf (67.26 KB)
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2007

Authors

Geier, Mark Steven

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The primary aim of this thesis was to identify probiotics and/or prebiotics with the potential to reduce the severity of experimental colitis. The specific aims were to i) screen a range of candidate pro biotic strains for capacity to reduce symptoms of DSS-colitis, ii) characterize the effects of DSS within the small intestine, iii) assess, in vitro, the effect of probiotics on intestinal epithelial cell integrity, iv) assess the potential for the prebiotic, fructooligosaccharide, to reduce the severity of DSS-colitis alone, and in synbiotic combination with a probiotic strain.

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School of Molecular and Biomedical Science : Physiology

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Thesis (Ph.D.) -- University of Adelaide, School of Molecular and Biomedical Sciences, 2007

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Title page, table of contents and abstract only. The complete thesis in print form is available from the University of Adelaide Library.

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