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Treating rheumatoid arthritis to target: physician and patient adherence issues in contemporary rheumatoid arthritis therapy

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dc.contributor.authorWabe, N.
dc.contributor.authorWiese, M.D.
dc.date.issued2017
dc.description.abstractDevelopment of the treat-to-target (T2T) strategy, the process whereby drug therapy is adjusted until the therapeutic goal is achieved, has revolutionized how rheumatoid arthritis (RA) patients are treated. With the advent of T2T, the management of RA is more effective than ever, with the possibility of remission and other favorable clinical and patient-reported outcomes. Effective implementation of a T2T strategy in routine clinical practice mainly depends on the long-term commitment of physician and patient to T2T treatment recommendations. However, as T2T is a complex process involving aggressive early management with several steps of therapy modifications requiring frequent close monitoring of disease activity and drug toxicities, it may be more liable to suboptimal adherence in real-life clinical practice. The aim of the review is to present key issues related to patient medication adherence and physician adherence to the current RA treatment recommendations and their importance in optimizing the outcome of treatment in RA treated according to T2T strategy.
dc.identifier.citationJournal of Evaluation in Clinical Practice, 2017; 23(3):486-493
dc.identifier.doi10.1111/jep.12620
dc.identifier.issn1356-1294
dc.identifier.issn1365-2753
dc.identifier.urihttps://hdl.handle.net/11541.2/123769
dc.language.isoen
dc.publisherWiley
dc.rightsCopyright 2016 Wiley
dc.source.urihttp://dx.doi.org/10.1111/jep.12620
dc.subjectmedication adherence
dc.subjectphysician adherence
dc.subjecttreat to target
dc.subjecttreatment outcome
dc.titleTreating rheumatoid arthritis to target: physician and patient adherence issues in contemporary rheumatoid arthritis therapy
dc.typeJournal article
pubs.publication-statusPublished
ror.mmsid9916105205401831

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