The use of probiotics in intestinal protection / by Emma Southcott.
Date
2002
Authors
Southcott, Emma K. (Emma Kate)
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Advisors
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Thesis
Citation
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Abstract
While studies have suggested that gastrointestinal pathogenicity associated with conditions such as inflammatory bowel disease and chemotherapy induced mucositis can be improved by the use of probiotics, the mechanisms of probiotic protection are not clearly understood. Such knowledge is necessary to achieve maximum benefit from such forms of treatment. This thesis describes investigations undertaken, initially to establish a non-invasive measure of intestinal barrier function, and then to examine the protective effects of different yoghurts on conditions which cause loss of barrier function: chemotherapy induced mucositis, inflammatory bowel disease and athletes in training. It was found that the function of the small intestine can be compromised under stress and that probiotics may improve compromised intestines through enhancing recovery of the intestinal mucosa and the barrier function.
School/Discipline
Dept. of Physiology
Dissertation Note
Thesis (Ph.D.)--University of Adelaide, Dept. of Physiology, 2002
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This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exception. If you are the author of this thesis and do not wish it to be made publicly available, or if you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at: http://www.adelaide.edu.au/legals
Description
Bibliography: leaves 154-199.
x, 199 leaves : ill. (some col.) ; 30 cm.
x, 199 leaves : ill. (some col.) ; 30 cm.