A simple formula for dielectric polaristion energies : the sheffield Solvation Model.

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2007

Authors

Grant, J.
Pickup, B.
Sykes, M.J.
Kitchen, C.
Nicholls, A.

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Chemical Physics Letters, 2007; 441(1-3):163-166

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This work introduces the 'Sheffield Solvation' model for calculating the electrostatic component of molecular solvation energy. The resulting formula can be included in standard modelling technology with very low computational cost. The model replaces detailed information about local atomic environments (such as found in Generalised Born approaches), by using two global parameters. The methodology is validated against accurate Poisson-Boltzmann calculations, and compared to Generalised Born results. © 2007 Elsevier B.V. All rights reserved.

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