Current studentsExisting staffContact us
 

Obstructive sleep apnoea in adults

Simple item page
dc.contributor.authorUsmani, Z.
dc.contributor.authorChai-Coetzer, C.
dc.contributor.authorAntic, N.
dc.contributor.authorMcEvoy, R.
dc.date.issued2013
dc.description.abstractObstructive sleep apnoea (OSA) is characterised by repetitive closure of the upper airway, repetitive oxygen desaturations and sleep fragmentation. The prevalence of adult OSA is increasing because of a worldwide increase in obesity and the ageing of populations. OSA presents with a variety of symptoms the most prominent of which are snoring and daytime tiredness. Interestingly though, a significant proportion of OSA sufferers report little or no daytime symptoms. OSA has been associated with an increased risk of cardiovascular disease, cognitive abnormalities and mental health problems. Randomised controlled trial evidence is awaited to confirm a causal relationship between OSA and these various disorders. The gold standard diagnostic investigation for OSA is overnight laboratory-based polysomnography (sleep study), however, ambulatory models of care incorporating screening questionnaires and home sleep studies have been recently evaluated and are now being incorporated into routine clinical practice. Patients with OSA are very often obese and exhibit a range of comorbidities, such as hypertension, depression and diabetes. Management, therefore, needs to be based on a multidisciplinary and holistic approach which includes lifestyle modifications. Continuous positive airway pressure (CPAP) is the first-line therapy for severe OSA. Oral appliances should be considered in patients with mild or moderate disease, or in those unable to tolerate CPAP. New, minimally invasive surgical techniques are currently being developed to achieve better patient outcomes and reduce surgical morbidity. Successful long-term management of OSA requires careful patient education, enlistment of the family's support and the adoption of self-management and patient goal-setting principles.
dc.description.statementofresponsibilityZafar Ahmad Usmani, Ching Li Chai-Coetzer, Nick A Antic, R Doug McEvoy
dc.identifier.citationPostgraduate Medical Journal, 2013; 89(1049):148-156
dc.identifier.doi10.1136/postgradmedj-2012-131340
dc.identifier.issn0032-5473
dc.identifier.issn1469-0756
dc.identifier.orcidMcEvoy, R. [0000-0002-5759-0094]
dc.identifier.urihttp://hdl.handle.net/2440/78987
dc.language.isoen
dc.publisherBritish Med Journal Publ Group
dc.rightsCopyright status unknown
dc.source.urihttps://doi.org/10.1136/postgradmedj-2012-131340
dc.subjectHumans
dc.subjectSleep Apnea, Obstructive
dc.subjectCardiovascular Diseases
dc.subjectObesity
dc.subjectSnoring
dc.subjectPolysomnography
dc.subjectContinuous Positive Airway Pressure
dc.subjectAdult
dc.subjectPatient Education as Topic
dc.subjectRandomized Controlled Trials as Topic
dc.titleObstructive sleep apnoea in adults
dc.typeJournal article
pubs.publication-statusPublished

Files

Collections

Medicine publications