A convenient synthesis of 5-alkylbicyclo[3.1.0]hexan-2-ones including the natural product sabina ketone
Date
1987
Authors
Hamon, D.P.
Shirley, N.J.
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Australian Journal of Chemistry: an international journal for chemical science, 1987; 40(7):1321-1325
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David P. G. Hamon and Neil J. Shirley
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Abstract
Simple 5-alkylbicyclo[3.1.0]hexan-2-ones, including the natural product sabina ketone, can be prepared in four steps from aromatic ethers via Birch reduction, hydrogen chloride addition, hydrolysis and then base treatment of the resultant 4-chlorocyclohexanones.
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© CSIRO 1987