Chronic myeloid leukemia: the basis of treatment for tomorrow

Date

2011

Authors

Carella, A.M.
Goldman, J.M.
Martinelli, G.
Melo, J.V.
Perrotti, D.

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Journal article

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Haematologica: the hematology journal, 2011; 96(12):1737-1739

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Angelo M. Carella, John M. Goldman, Giovanni Martinelli, Junia V. Melo, Danilo Perrotti

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Abstract

Recent years have seen dramatic advances in deciphering the molecular pathogenesis of chronic myeloid leukemia (CML). This has resulted in the rapid development of many BCR-ABL1-specific tyrosine kinase inhibitors (TKI) which have improved 10-year survival to more than 80%. In this paper we focus on some future directions for CML biology and therapy.

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Copyright © Ferrata Storti Foundation

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