Autoaugmentation gastrocystoplasty and demucosalized gastrocystoplasty in a sheep model

dc.contributor.authorDewan, P.
dc.contributor.authorStefanek, W.
dc.contributor.authorLorenz, C.
dc.contributor.authorOwen, A.
dc.contributor.authorByard, R.
dc.date.issued1995
dc.description.abstract<h4>Objectives</h4>To compare the normal sheep bladder at 6 and 12 months with bladders subjected to either an autoaugmentation gastrocystoplasty or a clam demucosalized gastrocystoplasty.<h4>Methods</h4>Twenty male lambs aged between 8 and 10 weeks had an autoaugmentation gastrocystoplasty in which de-epithelialized stomach muscle was added to an intact urothelium. The functional, radiologic, and histologic outcomes were compared with 11 animals who underwent a clam demucosalized gastrocystoplasty and 14 control animals. A total of 18 operated animals had a urodynamic study at 6 months and 9 at 12 months.<h4>Results</h4>The average bladder volume for the autoaugmentation gastrocystoplasty group at 12 months was greater than that of the control group (401 +/- 120 mL versus 205 +/- 77 mL). The demucosalized clam bladders had been less effectively enlarged (286 +/- 77 mL). The compliance values for autoaugmentation gastrocystoplasty animals were 14.7 +/- 11.3 mL/cm water (H2O) compared with 9.0 +/- 4.8 mL/cm H2O in the demucosalized gastrocystoplasty group, and 9.1 +/- 3.7 mL/cm H2O for the control animals.<h4>Conclusions</h4>The addition of the autoaugmentation procedure improves the prospect of enlarging the normal sheep bladder when using demucosalized gastric muscle.
dc.description.statementofresponsibilityP.A. Dewan, W. Stefanek, C. Lorenz, A.J. Owen, R.W. Byard
dc.identifier.citationUrology, 1995; 45(2):291-295
dc.identifier.doi10.1016/0090-4295(95)80020-4
dc.identifier.issn0090-4295
dc.identifier.issn1527-9995
dc.identifier.orcidByard, R. [0000-0002-0524-5942]
dc.identifier.urihttp://hdl.handle.net/2440/7891
dc.language.isoen
dc.publisherElsevier Science
dc.source.urihttps://doi.org/10.1016/0090-4295(95)80020-4
dc.subjectStomach
dc.subjectGastric Mucosa
dc.subjectAnimals
dc.subjectSheep
dc.subjectRadiography
dc.subjectMale
dc.subjectUrinary Bladder
dc.titleAutoaugmentation gastrocystoplasty and demucosalized gastrocystoplasty in a sheep model
dc.typeJournal article
pubs.publication-statusPublished

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