Information generation and processing systems that regulate periodontal structure and function

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dc.contributor.authorBartold, P.M.
dc.contributor.authorMcCulloch, C.A.
dc.date.issued2013
dc.descriptionArticle first published online: 11 AUG 2013
dc.description.abstractThe periodontium is a very dynamic organ that responds rapidly to mechanical and chemical stimuli. It is very complex in that it is composed of two hard tissues (cementum and bone) and two soft connective tissues (periodontal ligament and gingiva). Together these tissues are defined by the molecules expressed by the resident periodontal cells in each compartment and this determines not only the structure and function of the periodontium but also how it responds to infection and inflammation. The biological activity of these molecules is tightly regulated in time and space to preserve tissue homeostasis, influence inflammatory responses and participate in tissue regeneration. In this issue of Periodontology 2000 we explore new experimental approaches and data sets which help to understand the molecules and cells that regulate tissue form and structure in health, disease and regeneration.
dc.description.statementofresponsibilityP. Mark Bartold and Christopher A. McCulloch
dc.identifier.citationPeriodontology 2000, 2013; 63(1):7-13
dc.identifier.doi10.1111/prd.12037
dc.identifier.issn0906-6713
dc.identifier.issn1600-0757
dc.identifier.orcidBartold, P.M. [0000-0002-5695-3877] [0000-0002-6225-3084]
dc.identifier.urihttp://hdl.handle.net/2440/87060
dc.language.isoen
dc.publisherWiley
dc.rights© 2013 John Wiley & Sons A/S
dc.source.urihttps://doi.org/10.1111/prd.12037
dc.subjectAlveolar Process
dc.subjectNeutrophils
dc.subjectExtracellular Matrix
dc.subjectMesenchymal Stem Cells
dc.subjectPeriodontium
dc.subjectDental Cementum
dc.subjectGingiva
dc.subjectPeriodontal Ligament
dc.subjectHumans
dc.subjectBiofilms
dc.subjectPeriodontal Diseases
dc.subjectPeriodontitis
dc.subjectAntimicrobial Cationic Peptides
dc.subjectIntegrins
dc.subjectInflammation Mediators
dc.subjectGuided Tissue Regeneration, Periodontal
dc.subjectTissue Engineering
dc.subjectRegeneration
dc.subjectGene Expression Regulation
dc.subjectTooth Calcification
dc.subjectHomeostasis
dc.subjectSynthetic Biology
dc.subjectBiomechanical Phenomena
dc.titleInformation generation and processing systems that regulate periodontal structure and function
dc.typeJournal article
pubs.publication-statusPublished

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