Study of substrate-directed ordering of long double-stranded DNA molecules on bare highly oriented pyrolytic graphite surface based on atomic force microscopy relocation imaging

Date

2008

Authors

Wang, H.
An, H.
Zhang, F.
Zhang, Z.
Ye, M.
Xiu, P.
Zhang, Y.
Hu, J.

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Journal article

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Journal of Vacuum Science and Technology Part B: Nanotechnology and Microelectronics, 2008; 26(5):L41-L44

Statement of Responsibility

Huabin Wang, Hongjie An, Feng Zhang, Zhixiang Zhang, Ming Ye, Peng Xiu, Yi Zhang, Jun Hu

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Abstract

<jats:p>Usually, long double-stranded DNA molecules exhibit an aggregated or a random spreading behavior when deposited on a highly ordered pyrolytic graphite (HOPG) substrate. In this article, the authors report a novel phenomenon where randomly oriented DNA strands can gradually be rearranged into two-dimensional ordered nanostructures under the operation of repeatedly rotating a water droplet on the DNA sample. The process of DNA rearrangement was traced by using atomic force microscopy relocation imaging. The orientation of the ordered DNA strands shows a threefold symmetry consistent with the underlying atomic lattice of the HOPG substrate, signifying a substrate-directed ordering process. The relevant mechanism is discussed.</jats:p>

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2008 American Vacuum Society

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