Mouth dissolving tablet: superlative conclusive dosage in solid form for modern age
Date
2013
Authors
Kathawala, K.J.
Parikh, A.Y.
Inamdar, B.P.
Shah, S.G.
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Journal article
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Pharma science monitor, 2013; 4(4):416-437
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Abstract
Regardless of different advancement in drug delivery system, oral route remains the perfect route for the administration of the any therapeutic agents because of the low cost of therapy, ease of administration, self medication, and patient compliance. MDTs have received a great demand during the last decade because MDTs are dissolving rapidly in saliva without need of water, overcome the problem of Dysphasia i.e difficulty in swallowing and provides quick onset of action. Some tablets are designed to dissolve very fast within a few seconds are known as true FDTs. Fast or Mouth dissolving tablets are basically formulated for pediatric, geriatric, and bedridden patients and for active patients who are busy and travelling and may not have access to the water. In this review article, various conventional technologies like Freeze drying, Tablet Molding, Spray Drying, direct compression and patented technologies like Zydis, Orasolv, Durasolv, Flash tab, WOW Tab, Pharma burst etc are described to formulate MDTs. Moreover,various excipients used to formulate MDTs, how to develop the taste for the drugs having bitter taste, and how to conduct characterization and evaluations of MDTs are also described
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Copyright 2013 The Authors