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Critical insights to COVID-19 disease and potential treatments using a systems analysis approach that integrates physiology, pharmacology, and clinical pharmacology

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dc.contributor.authorMartin, J.H.
dc.contributor.authorHead, R.J.
dc.date.issued2022
dc.description.abstractThe power of pharmacology and its application by way of clinical pharmacology to provide invaluable insights into COVID-19 disease is brought home vividly when exploring the infectivity and pathophysiology of SARS-COV-2 in this pandemic. At its core, pharmacology utilizes and displays systems analysis to identify and correct aberrant physiology in disease or to provide much needed bridging intervention in a crisis. Pharmacology describes the impact of exogenous molecules upon living systems and to achieve this the discipline has over decades developed sophisticated measures to monitor absorption, distribution, excretion, and kinetics of interaction with the principal influenced tissues and receptors.
dc.identifier.citationPharmacology Research & Perspectives, 2022; 10(1, article no. e00918):1-3
dc.identifier.doi10.1002/prp2.918
dc.identifier.issn2052-1707
dc.identifier.issn2052-1707
dc.identifier.orcidHead, R.J. [0000-0002-1196-0926]
dc.identifier.urihttps://hdl.handle.net/11541.2/30208
dc.language.isoen
dc.publisherJohn Wiley & Sons
dc.rightsCopyright 2022 The authors. This is an open access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/)
dc.source.urihttps://doi.org/10.1002/prp2.918
dc.subjectCOVID-19
dc.subjectSARS-COV-2
dc.subjectpharmacology
dc.subjectviral infection
dc.subjectpassage
dc.subjectpathophysiology
dc.subjectHumans
dc.subjectPharmacology, Clinical
dc.subjectSystems Analysis
dc.titleCritical insights to COVID-19 disease and potential treatments using a systems analysis approach that integrates physiology, pharmacology, and clinical pharmacology
dc.typeJournal article
pubs.publication-statusPublished
ror.fileinfo12249820030001831 13305829260001831 9916608950401831
ror.mmsid9916608950401831

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