Predicting infections after total joint arthroplasty using a prescription based comorbidity measure

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dc.contributor.authorInacio, M.C.S.
dc.contributor.authorPratt, N.L.
dc.contributor.authorRoughead, E.E.
dc.contributor.authorGraves, S.E.
dc.date.issued2015
dc.description.abstractThis study evaluated the association and predictive ability of co-morbidities measured by RxRisk-V, Elixhauser and Charlson measures and post-total hip (THA) and total knee arthroplasties (TKA) infection. THAs and TKAs (2001–2012) were identified using the Australian Department of Veterans’ Affairs data. Infections within 90 days post-surgery were the study endpoint. Co-morbidities were identified using pharmacy (RxRisk-V) and hospitalization history (Elixhauser, Charlson). Of the 11,848 THAs, 3.1% (N = 364) had infections and out of 18,972 TKAs 3.4% (N = 648). Comorbidity burden and specific conditions were associated with infection likelihood. RxRisk-V performed better than other measures, but none had high predictive ability and differences were small. The best performing infection prediction models resulted when a combination of conditions identified by all measures was used.
dc.description.statementofresponsibilityMaria C.S.Inacio, Nicole L.Pratt, Elizabeth E.Roughead, Stephen E.Graves ... et al.
dc.identifier.citationJournal of Arthroplasty, 2015; 30(10):1692-1698
dc.identifier.doi10.1016/j.arth.2015.05.004
dc.identifier.issn0883-5403
dc.identifier.issn1532-8406
dc.identifier.orcidPratt, N.L. [0000-0001-8730-8910]
dc.identifier.orcidGraves, S.E. [0000-0002-1629-319X]
dc.identifier.urihttps://hdl.handle.net/2440/133643
dc.language.isoen
dc.publisherElsevier
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/1040938
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/1035889
dc.rights© 2015 Elsevier Inc. All rights reserved.
dc.source.urihttps://doi.org/10.1016/j.arth.2015.05.004
dc.subjectco-morbidities; total knee arthroplasty; total hip arthroplasty; RxRisk-V; pharmacy data
dc.subject.meshHumans
dc.subject.meshProsthesis-Related Infections
dc.subject.meshArthroplasty, Replacement, Hip
dc.subject.meshArthroplasty, Replacement, Knee
dc.subject.meshRetrospective Studies
dc.subject.meshComorbidity
dc.subject.meshAged
dc.subject.meshAged, 80 and over
dc.subject.meshAustralia
dc.subject.meshFemale
dc.subject.meshMale
dc.subject.meshDrug Prescriptions
dc.titlePredicting infections after total joint arthroplasty using a prescription based comorbidity measure
dc.typeJournal article
pubs.publication-statusPublished

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