Synteny and chromosome evolution in the lepidoptera: evidence from mapping in Heliconius melpomene

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dc.contributor.authorPringle, E.
dc.contributor.authorBaxter, S.
dc.contributor.authorWebster, C.
dc.contributor.authorPapanicolaou, A.
dc.contributor.authorLee, S.
dc.contributor.authorJiggins, C.
dc.date.issued2007
dc.description.abstractThe extent of conservation of synteny and gene order in the Lepidoptera has been investigated previously only by comparing a small subset of linkage groups between the moth Bombyx mori and the butterfly Heliconius melpomene. Here we report the mapping of 64 additional conserved genes in H. melpomene, which contributed 47 markers to a comparative framework of 72 orthologous loci spanning all 21 H. melpomene chromosomes and 27 of the 28 B. mori chromosomes. Comparison of the maps revealed conserved synteny across all chromosomes for the 72 loci, as well as evidence for six cases of chromosome fusion in the Heliconius lineage that contributed to the derived 21-chromosome karyotype. Comparisons of gene order on these fused chromosomes revealed two instances of colinearity between H. melpomene and B. mori, but also one instance of likely chromosomal rearrangement. B. mori is the first lepidopteran species to have its genome sequenced, and the finding that there is conserved synteny and gene order among Lepidoptera indicates that the genomic tools developed in B. mori will be broadly useful in other species.
dc.description.statementofresponsibilityElizabeth G. Pringle, Simon W. Baxter, Claire L. Webster, Alexie Papanicolaou, Siu F. Lee and Chris D. Jiggins
dc.identifier.citationGenetics: a periodical record of investigations bearing on heredity and variation, 2007; 177(1):417-426
dc.identifier.doi10.1534/genetics.107.073122
dc.identifier.issn0016-6731
dc.identifier.issn0016-6731
dc.identifier.orcidBaxter, S. [0000-0001-5773-6578]
dc.identifier.urihttp://hdl.handle.net/2440/76276
dc.language.isoen
dc.publisherGenetics
dc.rightsCopyright © 2007 by the Genetics Society of America
dc.source.urihttps://doi.org/10.1534/genetics.107.073122
dc.subjectChromosomes
dc.subjectAnimals
dc.subjectLepidoptera
dc.subjectButterflies
dc.subjectBombyx
dc.subjectChromosome Mapping
dc.subjectGene Rearrangement
dc.subjectSynteny
dc.subjectGene Order
dc.subjectGenome
dc.subjectMolecular Sequence Data
dc.subjectBiological Evolution
dc.subjectGenetic Linkage
dc.titleSynteny and chromosome evolution in the lepidoptera: evidence from mapping in Heliconius melpomene
dc.typeJournal article
pubs.publication-statusPublished

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