Identification of a parathyroid hormone in the fish Fugu rubripes

Date

2003

Authors

Danks, J.
Ho, P.
Notini, A.
Katsis, F.
Hoffmann, P.
Kemp, B.
Martin, T.
Zajac, J.

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Journal of Bone and Mineral Research, 2003; 18(7):1326-1331

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Abstract

A PTH gene has been isolated from the fish Fugu rubripes. The encoded protein of 80 amino acid has the lowest homology with any of the PTH family members. Fugu PTH(1-34) had 5-fold lower potency than human PTH(1-34) in a mammalian cell system.

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