Current studentsExisting staffContact us
 

Pneumocystis carinii pneumonia in childhood systemic lupus erythematosus

Simple item page
dc.contributor.authorFoster, H.
dc.contributor.authorMalleson, P.
dc.contributor.authorPetty, R.
dc.contributor.authorRoberton, D.
dc.contributor.authorCabral, D.
dc.date.issued1996
dc.description.abstract<h4>Objective</h4>Although Pneumocystis carinii pneumonia (PCP) is known to occur in adults with systemic lupus erythematosus (SLE), this infection has rarely been described in childhood SLE. We describe 3 children with SLE who developed PCP and describe risk factors for this complication.<h4>Methods</h4>A retrospective case review.<h4>Results</h4>All 3 children had severe active SLE with organ involvement requiring immunosuppressive therapy, but the clinical presentations of PCP differed in each patient. They shared some of the known risk factors for opportunistic infection in adults with SLE, including lymphopenia, but severe lymphopenia (< 0.35 x 10(9)/1) was not seen.<h4>Conclusion</h4>PCP is an uncommon but serious complication of childhood SLE, and should be considered in the presence of respiratory symptoms, however subtle. The role of oral chemoprophylaxis is discussed.
dc.identifier.citationJournal of Rheumatology, 1996; 23(4):753-756
dc.identifier.issn0315-162X
dc.identifier.issn1499-2752
dc.identifier.urihttp://hdl.handle.net/2440/7633
dc.language.isoen
dc.publisherJ RHEUMATOL PUBL CO
dc.subjectLung
dc.subjectHumans
dc.subjectPneumocystis
dc.subjectPneumonia, Pneumocystis
dc.subjectLupus Erythematosus, Systemic
dc.subjectImmunosuppressive Agents
dc.subjectAnti-Bacterial Agents
dc.subjectFatal Outcome
dc.subjectRisk Factors
dc.subjectRetrospective Studies
dc.subjectAdolescent
dc.subjectChild
dc.subjectFemale
dc.subjectTrimethoprim, Sulfamethoxazole Drug Combination
dc.titlePneumocystis carinii pneumonia in childhood systemic lupus erythematosus
dc.typeJournal article
pubs.publication-statusPublished

Files

Collections

Paediatrics publications