Genetic dissection of barley morphology and development

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dc.contributor.authorDruka, A.
dc.contributor.authorFranckowiak, J.
dc.contributor.authorLundqvist, U.
dc.contributor.authorBonar, N.
dc.contributor.authorAlexander, J.
dc.contributor.authorHouston, K.
dc.contributor.authorRadovic, S.
dc.contributor.authorShahinnia, F.
dc.contributor.authorVendramin, V.
dc.contributor.authorMorgante, M.
dc.contributor.authorStein, N.
dc.contributor.authorWaugh, R.
dc.date.issued2011
dc.description.abstractSince the early 20th century, barley (Hordeum vulgare) has been a model for investigating the effects of physical and chemical mutagens and for exploring the potential of mutation breeding in crop improvement. As a consequence, extensive and well-characterized collections of morphological and developmental mutants have been assembled that represent a valuable resource for exploring a wide range of complex and fundamental biological processes. We constructed a collection of 881 backcrossed lines containing mutant alleles that induce a majority of the morphological and developmental variation described in this species. After genotyping these lines with up to 3,072 single nucleotide polymorphisms, comparison to their recurrent parent defined the genetic location of 426 mutant alleles to chromosomal segments, each representing on average <3% of the barley genetic map. We show how the gene content in these segments can be predicted through conservation of synteny with model cereal genomes, providing a route to rapid gene identification.
dc.description.statementofresponsibilityArnis Druka, Jerome Franckowiak, Udda Lundqvist, Nicola Bonar, Jill Alexander, Kelly Houston, Slobodanka Radovic, Fahimeh Shahinnia, Vera Vendramin, Michele Morgante, Nils Stein and Robbie Waugh
dc.identifier.citationPlant Physiology, 2011; 155(2):617-627
dc.identifier.doi10.1104/pp.110.166249
dc.identifier.issn1532-2548
dc.identifier.issn1532-2548
dc.identifier.urihttp://hdl.handle.net/2440/88360
dc.language.isoen
dc.publisherAmerican Society of Plant Biologists
dc.rightsCopyright © 2011 by the American Society of Plant Biologists
dc.source.urihttps://doi.org/10.1104/pp.110.166249
dc.subjectHordeum
dc.subjectOryza sativa
dc.subjectDNA, Plant
dc.subjectChromosome Mapping
dc.subjectCrosses, Genetic
dc.subjectGenomics
dc.subjectSynteny
dc.subjectGenotype
dc.subjectMutation
dc.subjectPolymorphism, Single Nucleotide
dc.subjectAlleles
dc.subjectGenes, Plant
dc.titleGenetic dissection of barley morphology and development
dc.typeJournal article
pubs.publication-statusPublished

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