Un-promoted Issues in Inflammatory Bowel Disease (IBD): Opportunities to Optimise Care

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dc.contributor.authorAndrews, J.
dc.contributor.authorMountifield, R.
dc.contributor.authorVan Langenberg, D.
dc.contributor.authorBampton, P.
dc.contributor.authorHoltmann, G.
dc.date.issued2010
dc.descriptionArticle first published online: 22 OCT 2009
dc.description.abstractInflammatory bowel diseases (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), are chronic inflammatory disorders of the gut, which lead to significant morbidity and impaired quality of life (QoL) in sufferers, without generally affecting mortality. Despite CD and UC being chronic, life-long illnesses, most medical management is directed at acute flares of disease. Moreover, with more intensive medical therapy and the development of biological therapy, there is a risk that management will become even more narrowly focused on acute care, and be directed only at those with more severe disease, rather than encompassing all sufferers and addressing important non-acute issues. This imbalance of concentration of medical attention on 'high-end' care is in part driven by the need to perform and publish randomized clinical trials of newer therapies to obtain registration and licensing for these agents, which thus occupy a large proportion of the recent IBD treatment literature. This leads to less attention on relatively 'low-technology' issues including: (i) the psychosocial burden of chronic disease, QoL and specific psychological comorbidities; (ii) comorbidity with functional gastrointestinal disorders (FGIDs); (iii) maintenance therapy, monitoring and compliance; (iv) smoking (with regard to CD); (v) sexuality, fertility, family planning and pregnancy; and (vi) iron deficiency and anaemia. We propose these to be the 'Un-promoted Issues' in IBD and review the importance and treatment of each of these in the current management of IBD.
dc.description.statementofresponsibilityJane M. Andrews, Reme E. Mountifield, Daniel R. Van Langenberg, Peter A. Bampton, Gerald J. Holtmann
dc.identifier.citationInternal Medicine Journal, 2010; 40(3):173-182
dc.identifier.doi10.1111/j.1445-5994.2009.02110.x
dc.identifier.issn1444-0903
dc.identifier.issn1445-5994
dc.identifier.orcidAndrews, J. [0000-0001-7960-2650]
dc.identifier.urihttp://hdl.handle.net/2440/54902
dc.language.isoen
dc.publisherBlackwell Publishing Asia
dc.rights© 2010 The Authors. Journal compilation © 2010 Royal Australasian College of Physicians
dc.source.urihttps://doi.org/10.1111/j.1445-5994.2009.02110.x
dc.subjectHumans
dc.subjectColitis, Ulcerative
dc.subjectInflammatory Bowel Diseases
dc.subjectCrohn Disease
dc.subjectPatient Care
dc.subjectComorbidity
dc.subjectQuality of Life
dc.subjectDisease Management
dc.subjectRandomized Controlled Trials as Topic
dc.titleUn-promoted Issues in Inflammatory Bowel Disease (IBD): Opportunities to Optimise Care
dc.typeJournal article
pubs.publication-statusPublished

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