Toward a universal unit for quantification of antibiotic resistance genes in environmental samples
Date
2023
Authors
Yin, X.
Chen, X.
Jiang, X.T.
Yang, Y.
Ashbolt, N.J.
Zhang, T.
Editors
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Journal article
Citation
Environmental Science and Technology, 2023; 57(26):9713-9721
Statement of Responsibility
Conference Name
Abstract
Surveillance of antibiotic resistance genes (ARGs) has been increasingly conducted in environmental sectors to complement the surveys in human and animal sectors under the “One-Health” framework. However, there are substantial challenges in comparing and synthesizing the results of multiple studies that employ different test methods and approaches in bioinformatic analysis. In this article, we consider the commonly used quantification units (ARG copy per cell, ARG copy per genome, ARG density, ARG copy per 16S rRNA gene, RPKM, coverage, PPM, etc.) for profiling ARGs and suggest a universal unit (ARG copy per cell) for reporting such biological measurements of samples and improving the comparability of different surveillance efforts.
School/Discipline
Dissertation Note
Provenance
Description
Access Status
Rights
Copyright 2023 American Chemical Society