GADD45A methylation predicts poor overall survival in acute myeloid leukemia and is associated with IDH1/2 and DNMT3A mutations
Date
2013
Authors
Perugini, M.
Iarossi, D.
Kok, C.
Cummings, N.
Diakiw, S.
Brown, A.
Danner, S.
Bardy, P.
To, L.
Wei, A.
Editors
Advisors
Journal Title
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Type:
Journal article
Citation
Leukemia, 2013; 27(7):1588-1592
Statement of Responsibility
M Perugini, DG Iarossi, CH Kok, N Cummings, SM Diakiw, AL Brown, S Danner, P Bardy, L Bik To, AH Wei, ID Lewis, and RJ D’Andrea
Conference Name
Abstract
Acute myeloid leukemia (AML) is a heterogeneous disease with variable treatment outcome. Despite recent advances in understanding the key molecular mechanisms of myeloid leukemogenesis, risk stratification remains imperfect, particularly in the intermediate risk group in which a large proportion of patients have a normal karyotype.
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© 2013 Macmillan Publishers Limited