Integrated sample preparation, reaction, and detection on a high-frequency centrifugal microfluidic platform
Date
2005
Authors
Steigert, J.
Grumann, M.
Brenner, T.
Mittenbuehler, K.
Nann, T.
Ruhe, J.
Moser, I.
Haerberle, S.
Riegger, L.
Riegler, J.
Editors
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Journal article
Citation
Journal of Laboratory Automation, 2005; 10(5):331-341
Statement of Responsibility
Conference Name
Abstract
<jats:p> We extend the toolbox of lab procedures in life sciences by development of centrifugal microfluidics for high-level process integration. This is accomplished by implementing novel functional principles for sedimentation, batch-mode mixing, frequency-dependent online flow control, and optical read-out, which can be integrated into a process chain. The modular centrifugal setup comprises a microstructured disposable polymer disk as well as a reusable spinning and detection unit. We successfully developed centrifugal microfluidic technologies, which are suitable for sample preparation, process engineering, personalized diagnostics, and hematology, on this platform. </jats:p>