Biologically active natural products: ochromycinone analogues and aurein peptides : a thesis presented for the degree of Doctor of Philosophy / by Tomas Rozek.
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Date
2000
Authors
Rozek, Tomas
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Thesis
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Abstract
Sixteen aurein peptides are present in the host defence secretion from the granular dorsal glands of the Green and Golden Bell Frog (Litoria aurea) and seventeen from those of the related Southern Bell Frog (Litoria raniformis). All peptides have been sequenced using a combination of electrospray mass spectrometry and Lys-C digestion, with each sequence confirmed by automated Edman sequencing. Ten of these peptides are common to both species of frog. Thirteen of the aurein peptides show wide-spectrum antibiotic and anticancer activity.
School/Discipline
Dept. of Chemistry
Dissertation Note
Thesis (Ph.D.)--Adelaide University, Dept. of Chemistry, 2001
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This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exception. If you are the author of this thesis and do not wish it to be made publicly available or If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at: http://www.adelaide.edu.au/legals. Copyright material removed from digital thesis. See print copy in University of Adelaide Library for full text.
Description
Includes copies of articles co-authored by the author during preparation of this thesis.
Includes bibliographical references (leaves 185-191).
v, 192 leaves : ill. ; 30 cm.
Includes bibliographical references (leaves 185-191).
v, 192 leaves : ill. ; 30 cm.