Palaeopathology of the earlobe crease (Frank's sign): new insights from Renaissance art
Date
2017
Authors
Galassi, F.
Borghi, C.
Ballestriero, R.
Habicht, M.
Henneberg, M.
Rühli, F.
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Journal article
Citation
International Journal of Cardiology, 2017; 236:82-84
Statement of Responsibility
Francesco M. Galassi, Claudio Borghi, Roberta Ballestriero, Michael E. Habicht, Maciej Henneberg, Frank J. Rühli
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Abstract
Several studies have associated the earlobe crease sign, discovered by Sanders T. Frank in 1973, with cardiovascular pathology, yet very few studies have focused on the antiquity of this trait, with the most ancient one thought to date back to the Roman Emperor Hadrian (76-138CE). This article presents two more cases from the Italian Renaissance in the works of the artist Andrea Mantegna (1431-1506) and examines them in a multidisciplinary fashion.
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© 2017 Elsevier B.V. All rights reserved.