Self-ordered nanopore and nanotube platforms for drug delivery applications

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dc.contributor.authorLosic, D.
dc.contributor.authorSimovic, S.
dc.date.issued2009
dc.description.abstractThe application of nanotechnology to medicine termed as ‘nanomedicine’ is recognised as an emerging field with enormous potential for developing new therapeutic concepts. A range of nanoscale materials have been explored in the last few years for drug delivery to address the problems associated with conventional drug therapies such as limited drug solubility, poor biodistribution, lack of selectivity and unfavourable pharmacokinetics. Among them, nanoporous materials with ordered and controlled pore structures, high surface area and pore volume, attracted great attention, particularly for implantable drug delivery systems. This review presents the recent progress in this field focused on electrochemically engineered nanopores/nanotube materials such as nanoporous alumina and nanotubular titania. The basic concept of fabrication of these unique materials using a self-ordering process, description of their structural properties, biocompatibility and recent applications for therapeutic implants is presented.
dc.description.statementofresponsibilityDusan Losic & Spomenka Simovic
dc.identifier.citationExpert Opinion on Drug Delivery, 2009; 6(12):1363-1381
dc.identifier.doi10.1517/17425240903300857
dc.identifier.issn1742-5247
dc.identifier.issn1744-7593
dc.identifier.orcidLosic, D. [0000-0002-1930-072X]
dc.identifier.urihttp://hdl.handle.net/2440/94024
dc.language.isoen
dc.publisherInforma Healthcare
dc.relation.grantARC
dc.rights© 2009 Informa UK Ltd
dc.source.urihttps://doi.org/10.1517/17425240903300857
dc.subjectdrug delivery; electrochemical anodisation; nanoporous alumina; nanotube titania
dc.titleSelf-ordered nanopore and nanotube platforms for drug delivery applications
dc.typeJournal article
pubs.publication-statusPublished

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