Physical inactivity is associated with moderate-severe obstructive sleep apnea

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dc.contributor.authorSimpson, L.
dc.contributor.authorMcArdle, N.
dc.contributor.authorEastwood, P.
dc.contributor.authorWard, K.
dc.contributor.authorCooper, M.
dc.contributor.authorWilson, A.
dc.contributor.authorHillman, D.
dc.contributor.authorPalmer, L.
dc.contributor.authorMukherjee, S.
dc.date.issued2015
dc.description.abstractStudy Objectives: To investigate whether low levels of physical activity were associated with an increased occurrence of obstructive sleep apnea (OSA), OSA-related symptoms, and cardiometabolic risk. Methods: A case-control study design was used. OSA cases were patients referred to a sleep clinic for suspected OSA (n = 2,340). Controls comprised participants from the Busselton community (n = 1,931). Exercise and occupational activity were derived from questionnaire data. Associations were modelled using logistic and linear regression and adjusted for confounders. Results: In comparison with moderate exercise, the high, low, and nil exercise groups had an odds ratio (OR) for moderate-severe OSA of 0.6 (95% CI 0.5–0.8), 1.6 (95% CI 1.2–2.0), and 2.7 (95% CI 1.9–3.7), respectively. Relative to men in heavy activity occupations, men in medium, light and sedentary occupations had an OR for moderate-severe OSA of 1.7 (95% CI 1.1–2.5), 2.1 (95% CI 1.4–3.2), and 1.8 (95% CI 1.2–2.8), respectively. Relative to women in medium activity occupations, women in light and sedentary occupations had an OR for moderate-severe OSA of 4.2 (95% CI 2.6–7.2) and 3.5 (2.0–6.0). OSA patients who adequately exercised had lower: levels of doctor-diagnosed depression (p = 0.047); symptoms of fatigue (p < 0.0001); systolic (p = 0.015) and diastolic blood pressure (p = 0.015); and C-reactive protein (CRP) (p = 0.003). Conclusions: Low levels of physical activity were associated with moderate-severe OSA. Exercise in individuals with OSA is associated with lower levels of depression, fatigue, blood pressure and CRP.
dc.description.statementofresponsibilityLaila Simpson, Nigel McArdle, Peter R. Eastwood, Kim L. Ward, Matthew N. Cooper, Annette C. Wilson, David R. Hillman, Lyle J. Palmer, Sutapa Mukherjee
dc.identifier.citationThe Journal of Clinical Sleep Medicine, 2015; 11(10):1091-1099A
dc.identifier.doi10.5664/jcsm.5078
dc.identifier.issn1550-9389
dc.identifier.issn1550-9397
dc.identifier.orcidPalmer, L. [0000-0002-1628-3055]
dc.identifier.urihttp://hdl.handle.net/2440/99760
dc.language.isoen
dc.publisherAmerican Academy of Sleep Medicine
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/1042341
dc.rightsCopyright status unknown
dc.source.urihttps://doi.org/10.5664/jcsm.5078
dc.subjectweight; sleep disordered breathing; cardio metabolic; occupation; exercise
dc.titlePhysical inactivity is associated with moderate-severe obstructive sleep apnea
dc.typeJournal article
pubs.publication-statusPublished

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