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Cabozantinib inhibits abiraterone's upregulation of IGFIR phosphorylation and enhances its anti-prostate cancer activity

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dc.contributor.authorWang, X.
dc.contributor.authorHuang, Y.
dc.contributor.authorChristie, A.
dc.contributor.authorBowden, M.
dc.contributor.authorLee, G.
dc.contributor.authorKantoff, P.
dc.contributor.authorSweeney, C.
dc.date.issued2015
dc.description.abstractAbstract not available
dc.description.statementofresponsibilityXiaodong Wang, Ying Huang, Amanda Christie, Michaela Bowden, Gwo-Shu Mary Lee, Philip W. Kantoff and Christopher J. Sweeney
dc.identifier.citationClinical Cancer Research, 2015; 21(24):5578-5587
dc.identifier.doi10.1158/1078-0432.CCR-15-0824
dc.identifier.issn1078-0432
dc.identifier.issn1557-3265
dc.identifier.orcidSweeney, C. [0000-0002-0398-6018]
dc.identifier.urihttp://hdl.handle.net/2440/103782
dc.language.isoen
dc.publisherAmerican Association for Cancer Research
dc.rights© 2015 American Association for Cancer Research
dc.source.urihttps://doi.org/10.1158/1078-0432.ccr-15-0824
dc.subjectCell Line, Tumor
dc.subjectAnimals
dc.subjectHumans
dc.subjectMice
dc.subjectProstatic Neoplasms
dc.subjectDisease Models, Animal
dc.subjectAnilides
dc.subjectPyridines
dc.subjectAndrostenes
dc.subjectReceptor Protein-Tyrosine Kinases
dc.subjectReceptor, IGF Type 1
dc.subjectReceptors, Androgen
dc.subjectAntineoplastic Agents
dc.subjectTumor Burden
dc.subjectXenograft Model Antitumor Assays
dc.subjectSignal Transduction
dc.subjectCell Proliferation
dc.subjectPhosphorylation
dc.subjectDrug Antagonism
dc.subjectDrug Resistance, Neoplasm
dc.subjectMale
dc.titleCabozantinib inhibits abiraterone's upregulation of IGFIR phosphorylation and enhances its anti-prostate cancer activity
dc.typeJournal article
pubs.publication-statusPublished

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