School of Medical Sciences
Permanent URI for this community
The School of Medical Sciences encompasses the disciplines of Anatomical Sciences, Pathology and Pharmacology.
Browse
Browsing School of Medical Sciences by Issue Date
Now showing 1 - 20 of 3067
Results Per Page
Sort Options
Item Metadata only Ovarian changes during pregnancy and pseudopregnancy in the vole, Microtus agrestis(Society for Reproduction and Fertility, 1970) Breed, W.G.; Clarke, J.R.In the vole, Microtus agrestis, there was no significant change in the number of corpora lutea (cl) during either pregnancy or pseudopregnancy. In pregnant animals, two waves of luteal development took place and histological changes during the two phases of growth differed. In pseudopregnant animals, a similar increase occurred initially which was followed by a marked decrease after Day 8, at which time cl began to degenerate. Luteinized follicles were visible early in pregnancy and pseudopregnancy. Graafian follicles were present after Day 2 or 3. In pregnant animals, the number remained more or less constant, except for a slight increase on Day 19, but their maximum size was reduced at about mid-term, whereas, in pseudopregnant animals, a marked increase in size occurred between Days 8 and 10. Vaginal smears and histology indicated progesterone secretion up to Day 19 of pregnancy and for the 8 to 9 days of pseudopregnancy. There was, therefore, a good correlation between the presence of healthy cl and smears that indicated progesterone secretion.Item Metadata only Reproductive possibilities and estimations of the biological dynamics of earlier human populations(Elsevier, 1976) Henneberg, M.Abstract not availableItem Metadata only Early embryonic development and ovarian activity during concurrent pregnancy and lactation in the hopping-mouse Notomys alexis(CSIRO Publishing, 1981) Breed, W.G.In the hopping-mouse, following a postpartum mating, embryos enter the uterus on about day 5. Implantation occurs on about day 7 if there are no suckling pups, but zona-free blastocysts may remain up to day 18 if from four to seven suckling pups are present. Implantation is eccentric and initially involves interdigitation of trophectoderm and uterine epithelial cells, followed by epithelial cell displacement. The orientation is antimesometrial and, during further development, the embryo invaginates into the yolk-sac cavity. In the ovary, corpora lutea develop during the first few days of pregnancy and then remain unchanged in size or cellular morphology until implantation, regardless of the length of its delay. Peripheral progesterone levels likewise show little change during the preimplantation period. After implantation, a similar number of corpora lutea are found but they increase progressively in size due to luteal cell hypertrophy. The cells show all the organelles typical of steroid hormone synthetic activity and there is a corresponding increase in blood progesterone levels at this time. Vesicular follicles are present throughout concurrent pregnancy and lactation and are larger after implantation. There is no evidence of spontaneous ovulation except at the time of parturition.Item Metadata only Variability in the clinical presentation and endoscopic findings of herpetic esophagitis(Georg Thieme Verlag KG, 1987) Byard, R.W.; Champion, M.C.; Orizaga, M.Three cases of herpetic esophagitis are reported in which the endoscopic features were non-specific and the triad of odynophagia, retrosternal pain and fever was absent, suggesting that the endoscopic and clinical presentation may be more variable than previously described.Item Metadata only Hypernoradrenergic innervation: Its relationship to functional and hyperplastic changes in the vasculature of the spontaneously hypertensive rat(Karger AG, 1989) Head, R.There is now compelling evidence indicating that there is a greater sympathetic innervation of blood vessels in the spontaneously hypertensive rat (SHR) when compared with the innervation of corresponding vessels in the normotensive genetic control rat (WKY). In selected vascular beds in the SHR, increased sympathetic innervation occurs immediately after birth and prior to the expression of hypertension in the animal. In contrast, the available evidence suggests that the sympathetic innervation of cardiac tissue in SHR and WKY are similar in young and adult rats. The functional significance of the enhanced sympathetic innervation of blood vessels in the SHR with regard to the development or maintenance of hypertension relates in two ways to the well-established phenomena of vascular smooth muscle cell hypertrophy and hyperplasia, which are thought to be the pathophysiological basis for the increased peripheral vascular resistance and elevated blood pressure in this animal model of hypertension. First, the enhanced innervation of blood vessels in the SHR leads to an augmented release of the vasoconstrictor transmitter noradrenaline (NA). The predicted consequences of this augmented release of NA upon vascular contraction are modulated by the presence of a larger number of sites for neuronal inactivation (i.e. reuptake sites) of NA by virtue of the presence of the increased innervation. Second, and of more significance, is the inter-relationship between hypernoradrenergic innervation and vascular smooth muscle hyperplasia, as the early appearance of such changes is a powerful indicator for the subsequent expression of hypertension in the SHR. In view of the substantial evidence that implicates vascular smooth muscle cells in regulating the degree of their sympathetic innervation and confirms the influence of sympathetic nerves upon vascular smooth muscle hyperplastic change, attention is drawn to the role of trophic factors in providing the setting for the development of hypertension in the SHR.Item Metadata only Sonographically demonstrated thickening of the renal pelvis in children(Springer Verlag, 1992) Alton, D.J.; Lequesne, G.W.; Gent, R.; Siegmann, J.W.; Byard, R.Thickening of the wall of the renal pelvis has been attributed to infection, to rejection in allografts and to non-specific causes by different authors. We reviewed the clinical data, imaging studies and pathology of 35 patients with sonographically demonstrable thickening in 41 renal pelves of native kidneys. Our findings are that less than 50% of the patients had infection. The others had a wide variety of apparent causes for the thickening which include obstruction, surgery, edema induced by chemicals and other processes. Vesicoureteral reflux was demonstrated in 50% of the patients studied by cystography. We concluded that renal pelvic thickening is a non-specific finding.Item Metadata only Autoerotic death - characteristic features and diagnostic difficulties(Elsevier BV, 1994) Byard, R.Autoerotic death refers to the accidental death of individuals of either sex due to failure of devices, or unexpected effect of materials, that were being used to enhance the sexual experience. Although asphyxia from hanging has been described most frequently, a wide variety of other lethal situations have been reported. As there is great variability in the number and types of sexual aids that may be used by individuals, careful death scene examination is essential in helping to exclude suicide and more rarely homicide. The clandestine nature of this paraphilia may, however, make subsequent identification and diagnosis difficult unless the death scene features are typical. This is particularly so in the rare cases involving women. In the following paper the typical features of this disorder are reviewed with a description of less obvious cases and possible diagnostic pitfalls.Item Metadata only First human culture-proven Australian case of entomophthoromycosis caused by Basidiobolus ranarum(Carfax, 1994) Davis, S.R.; Ellis, D.H.; Goldwater, P.; Dimitriou, S.; Byard, R.The first human case of entomophthoromycosis caused by Basidiobolus ranarum in Australia is described. Upon first presentation this rare disease was not recognized, but microscopy of biopsy sections and identification of the fungal isolate allowed this condition to be identified. Treatment with fluconazole was successful.Item Metadata only Haemophilia A management in Victorian, New South Wales and South Australian haemophilia centres(Australian Medical Publishing Co., 1995) Ekert, H.; Ekert, N. L.; Street, A. M.; Rickard, K. A.; McPherson, V. J.; Toogood, I. R. G.; Lloyd, J. V.Item Metadata only Unusual presentation of death due to carbon monoxide poisoning(Masson Publishing USA, Inc, 1995) Ruszkiewicz, A.; De Boer, B.; Robertson, S.Item Metadata only Spero-echinocytosis of human red blood cells caused by snake, red-back spider, bee and blue-ringed octopus venom and its inhibition by snake sera(Pergamon, Elsevier Science Ltd., 1995) Flachsenberger, F.; Leigh, C.; Mirtschin, P.Item Metadata only Sudden and unexpected death in infancy and early childhood - Diagnostic possibilities(The Law Book Company, 1995) Byard, R.Item Metadata only Paediatric neoplasia(1995) Byard, R.Item Metadata only Treating Hypertension in the Elderly(National Heart Foundation, 1995) Tonkin, Anne L.; School of Medical Sciences : PharmacologyItem Metadata only Endstubin: A marker antigen for the endocytic stage of intestinal development in rat, sheep and human(Raven Press, 1995) Trahair, J. F.; Wilson, J. M.; Neutra, M. R.Item Metadata only Experience of once-daily aminoglycoside dosing using a target area under the concentration-time curve(Royal Australasian College of Physicians, 1995) Barclay, Murray L.; Duffull, Stephen B.; Begg, Evan J.; Buttimore, R. C.; School of Medical Sciences : PharmacologyItem Metadata only Undiagnosed ponto medullary astocytoma: A history of speech pathology systems(Institute for Research on Teaching, Michigan State University, 1995) Warms, T.; Ruszkiewicz, A.; Opeskin, K.Item Metadata only Axonal injury by captive bolt impact in the sheep(Taylor & Francis, 1995) Lewis, S.; Blumbergs, P.; Reilly, P.; Scott, G.; Manavis, J.; Brown, C.; Finnie, J.; Jones, N.Item Metadata only Formation and reactivity of acyl-glucuronides: The influence of chirality(1995) Hayball, Peter JohnItem Metadata only The long-term effect of pinealectomy on the crypts of the rat gastrointestinal tract(Munksgaard, Denmark, 1995) Callaghan, Brian Desmond