2009 - Pushing the limits

Permanent URI for this collection

Browse

Recent Submissions

Now showing 1 - 20 of 20
  • ItemOpen Access
    The Global Prevalence and Severity of Dental Caries among Racially Minoritized Children: A Systematic Review and Meta-Analysis
    (Karger Publishers, 2023) Nath, S.; Sethi, S.; Bastos, J.L.; Constante, H.M.; Mejia, G.; Haag, D.; Kapellas, K.; Jamieson, L.
    Racially minoritized children often bear a greater burden of dental caries, but the overall magnitude of racial gaps in oral health and their underlying factors are unknown. A systematic review and meta-analysis were conducted to fill these knowledge gaps. We compared racially minoritized (E) children aged 5–11 years (P) with same-age privileged groups (C) to determine the magnitude and correlates of racial inequities in dental caries (O) in observational studies (S). Using the PICOS selection criteria, a targeted search was performed from inception to December 1, 2021, in nine major electronic databases and an online web search for additional grey literature. The primary outcome measures were caries severity, as assessed by mean decayed, missing, and filled teeth (dmft) among children and untreated dental caries prevalence (d > 0%). The meta-analysis used the random-effects model to calculate standardized mean differences (SMD) and 95% confidence intervals (95% CI). Subgroup analysis, tests for heterogeneity (I², Galbraith plot), leave-one-out sensitivity analysis, cumulative analysis, and publication bias (Egger’s test and funnel plots) tests were carried out. The New Castle Ottawa scale was used to assess risk of bias. This review was registered with PROSPERO, CRD42021282771. A total of 75 publications were included in the descriptive analysis. The SMD of dmft score was higher by 2.30 (95%CI: 0.45, 4.15), and the prevalence of untreated dental caries was 23% (95% CI: 16, 31) higher among racially minoritized children, compared to privileged groups. Cumulative analysis showed worsening caries outcomes for racially marginalized children over time and larger inequities in dmft among high-income countries. Our study highlights the high caries burden among minoritized children globally by estimating overall trends and comparing against factors including time, country, and world income. The large magnitude of these inequities, combined with empirical evidence on the oral health impacts of racism and other forms of oppression, reinforce that oral health equity can only be achieved with social and political changes at a global level.
  • ItemOpen Access
    Crosstalk between Dpp and Tor signaling coordinates autophagy-dependent midgut degradation
    (Nature Publishing Group, 2019) Denton, D.; Xu, T.; Dayan, S.; Nicolson, S.; Kumar, S.
    The majority of developmentally programmed cell death (PCD) is mediated by caspase-dependent apoptosis; however, additional modalities, including autophagy-dependent cell death, have important spatiotemporally restricted functions. Autophagy involves the engulfment of cytoplasmic components in a double membrane vesicle for delivery to the lysosome. An established model for autophagy-dependent PCD is Drosophila larval midgut removal during metamorphosis. Our previous work demonstrated that growth arrest is required to initiate autophagy-dependent midgut degradation and Target of rapamycin (Tor) limits autophagy induction. In further studies, we uncovered a role for Decapentaplegic (Dpp) in coordinating midgut degradation. Here, we provide new data to show that Dpp interacts with Tor during midgut degradation. Inhibiting Tor rescued the block in midgut degradation due to Dpp signaling. We propose that Dpp is upstream of Tor and down-regulation promotes growth arrest and autophagy-dependent midgut degradation. These findings underscore a relationship between Dpp and Tor signaling in the regulation of cell growth and tissue removal.
  • ItemOpen Access
    QCD evolution of the spin structure functions of the neutron and proton
    (American Physical Society, 1990) Schreiber, A.W.; Thomas, A.W.; Londergan, J.T.
    Models of the long-distance behavior of QCD can be used to make predictions for the twist-two piece of the current correlation function appearing in deep-inelastic scattering. The connection between the model predictions, valid at a four-momentum transfer squared Q2 of the order of 1 (GeV/c)2, and the data, collected at much higher Q2, is provided by perturbative QCD. We present here the details of a method, previously used for spin-averaged lepton scattering, applied to the spin-dependent case. We then use the method to make predictions for the spin structure functions gprotonl and gneutronl.
  • ItemOpen Access
    The place of work in a meaningful life
    (Radio Adelaide, 2009) Stott Despoja, Natasha; Megalogenis, George; Blackburn, Simon
    Adelaide Festival of Ideas session, Basil Hetzel Lecture Room, University of Adelaide, 3.00pm, Sunday 12th July, 2009. Chaired by Barbara Pocock.
  • ItemOpen Access
    Beyond Evolution
    (Radio Adelaide, 2009) Singh, Simon; McCalman, Iain; Lazcano, Antonio; Webb, Val
    Adelaide Festival of Ideas session, Elder Hall, University of Adelaide, 3.00pm, Sunday 12th July, 2009. Chaired by Ian Gibbins.
  • ItemOpen Access
    You’re disgusting! Shaming mechanisms in different cultures
    (Radio Adelaide, 2009) Gaita, Raimond; Hussein, Shakira; Schiebinger, Londa; Gelber, Katherine
    Adelaide Festival of Ideas session, Bonython Hall, University of Adelaide, 3.00pm, Sunday 12th July, 2009. Chaired by Robert Phiddian.
  • ItemOpen Access
    Darwin’s Armada: Pushing the intellectual boundaries from academe to trade book and TV series
    (Radio Adelaide, 2009) McCalman, Iain
    Adelaide Festival of Ideas session, Art Gallery Auditorium, Art Gallery of South Australia, 1.45pm, Sunday 12th July, 2009. Chaired by Margaret Anderson.
  • ItemOpen Access
    Reach for the stars: New directions in astronomy
    (Radio Adelaide, 2009) Webster, Rachel
    Adelaide Festival of Ideas session, Basil Hetzel Lecture Room, University of Adelaide, 1.45pm, Sunday 12th July, 2009. Chaired by Duncan Steele.
  • ItemOpen Access
    Life: its origin and evolution
    (Radio Adelaide, 2009) Lazcano, Antonio
    Adelaide Festival of Ideas session, Elder Hall, University of Adelaide, 1.45pm, Sunday 12th July, 2009. Chaired by Chris Burrell.
  • ItemOpen Access
    Joy MacLennan Oration – The idea of absolute value
    (Radio Adelaide, 2009) Gaita, Raimond
    Adelaide Festival of Ideas session, Bonython Hall, University of Adelaide, 1.45pm, Sunday 12th July, 2009. Chaired by Lyn Arnold.
  • ItemOpen Access
    You are not your brain scan!
    (Radio Adelaide, 2009) Mitchell, Natasha
    Adelaide Festival of Ideas session, Art Gallery Auditorium, Art Gallery of South Australia, 11.4am, Sunday 12th July, 2009. Chaired by Peter Mares.
  • ItemOpen Access
    The first and last century of global drug prohibition
    (Radio Adelaide, 2009) Wodak, Alex
    Adelaide Festival of Ideas session, Basil Hetzel Lecture Room, University of Adelaide, 11.45am, Sunday 12th July, 2009. Chaired by Rick Sarre.
  • ItemOpen Access
    Climate change beyond the city limits?
    (Radio Adelaide, 2009) Denniss, Richard; Mackey, Brendan; Miller, Suzanne
    Adelaide Festival of Ideas session, Elder Hall, University of Adelaide, 11:45am, Sunday 12th July, 2009. Chaired by Carol Vincent.
  • ItemOpen Access
    Talking in Tongues – the hopes and fears of interfaith dialogue
    (Radio Adelaide, 2009) Webb, Val; Bouma, Gary; Hussein, Shikara
    Adelaide Festival of Ideas session, Bonython Hall, University of Adelaide, 11.45am, Sunday 12th July, 2009. Chaired by Rev. Stephen Pickard.
  • ItemOpen Access
    Has corporate responsibility reached its limits?
    (Radio Adelaide, 2009) Shergold, Peter
    Adelaide Festival of Ideas session, Art Gallery Auditorium, Art Gallery of South Australia, 10.30am, Sunday 12th July, 2009. Chaired by Michael Barber.
  • ItemOpen Access
    Pushing the limits of a one-milligram brain: Vision, perception and ‘cognition’ in honeybees
    (Radio Adelaide, 2009) Srinivasan, Mandyam
    Adelaide Festival of Ideas session, Basil Hetzel Lecture Room, University of Adelaide, 10.30am, Sunday 12th July, 2009. Chaired by Ian Gibbins.
  • ItemOpen Access
    Why migrant smuggling pays
    (Radio Adelaide, 2009) Koser, Khalid
    Adelaide Festival of Ideas session, Elder Hall, University of Adelaide, 10:30am, Sunday 12th July, 2009. Chaired by Peter Mares.
  • ItemOpen Access
    Trick or Treatment? Alternative medicine on trial
    (Radio Adelaide, 2009) Singh, Simon
    Adelaide Festival of Ideas session, Bonython Hall, University of Adelaide, 10:30 am, Sunday 12th July 2009. Chaired by Duncan Steel.
  • ItemOpen Access
    Where do big ideas come from?
    (Radio Adelaide, 2009) Adams, Phillip; Petty, Bruce; Singh, Simon; Lazcano, Antonio; Webster, Rachel
    Adelaide Festival of Ideas session, Elder Hall, University of Adelaide, 8.10pm, Thursday 9th July, 2009. Chaired by Phillip Adams.
  • ItemOpen Access
    Phillip Adams to welcome the audience and acknowledge the Dedication to Frank Fenner
    (Radio Adelaide, 2009) Adams, Phillip
    Adelaide Festival of Ideas session, Elder Hall, University of Adelaide, 8.00pm, Thursday 9 July, 2009.