Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/2915
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Effect of a high-protein, energy-restricted diet on body composition, glycemic control, and lipid concentrations in overweight and obese hyperinsulinemic men and women |
Author: | Farnsworth, E. Luscombe-Marsh, N. Noakes, M. Wittert, G. Argyiou, E. Clifton, P. |
Citation: | American Journal of Clinical Nutrition, 2003; 78(1):31-39 |
Publisher: | Amer Soc Clinical Nutrition |
Issue Date: | 2003 |
ISSN: | 0002-9165 1938-3207 |
Statement of Responsibility: | Emma Farnsworth, Natalie D Luscombe, Manny Noakes, Gary Wittert, Eleni Argyiou and Peter M Clifton |
Abstract: | <h4>Background</h4>It is not clear whether varying the protein-to-carbohydrate ratio of weight-loss diets benefits body composition or metabolism.<h4>Objective</h4>The objective was to compare the effects of 2 weight-loss diets differing in protein-to-carbohydrate ratio on body composition, glucose and lipid metabolism, and markers of bone turnover.<h4>Design</h4>A parallel design included either a high-protein diet of meat, poultry, and dairy foods (HP diet: 27% of energy as protein, 44% as carbohydrate, and 29% as fat) or a standard-protein diet low in those foods (SP diet: 16% of energy as protein, 57% as carbohydrate, and 27% as fat) during 12 wk of energy restriction (6-6.3 MJ/d) and 4 wk of energy balance ( approximately 8.2 MJ/d). Fifty-seven overweight volunteers with fasting insulin concentrations > 12 mU/L completed the study.<h4>Results</h4>Weight loss (7.9 +/- 0.5 kg) and total fat loss (6.9 +/- 0.4 kg) did not differ between diet groups. In women, total lean mass was significantly (P = 0.02) better preserved with the HP diet (-0.1 +/- 0.3 kg) than with the SP diet (-1.5 +/- 0.3 kg). Those fed the HP diet had significantly (P < 0.03) less glycemic response at weeks 0 and 16 than did those fed the SP diet. After weight loss, the glycemic response decreased significantly (P < 0.05) more in the HP diet group. The reduction in serum triacylglycerol concentrations was significantly (P < 0.05) greater in the HP diet group (23%) than in the SP diet group (10%). Markers of bone turnover, calcium excretion, and systolic blood pressure were unchanged.<h4>Conclusion</h4>Replacing carbohydrate with protein from meat, poultry, and dairy foods has beneficial metabolic effects and no adverse effects on markers of bone turnover or calcium excretion. |
Keywords: | Humans Hyperinsulinism Insulin Resistance Obesity Blood Glucose Lipids Fatty Acids, Nonesterified Triglycerides Dietary Proteins Diet Body Composition Energy Intake Middle Aged Female Male Cholesterol, LDL Cholesterol, HDL |
Description: | Copyright © 2003 American Society for Clinical Nutrition |
DOI: | 10.1093/ajcn/78.1.31 |
Published version: | http://www.ajcn.org/cgi/content/abstract/78/1/31 |
Appears in Collections: | Aurora harvest 6 Medicine publications Molecular and Biomedical Science publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.