Distribution of the saa gene in strains of Shiga toxin-producing Escherichia coli of human and bovine origins
Date
2003
Authors
Jenkins, C.
Perry, N.
Cheasty, T.
Shaw, D.
Frankel, G.
Dougan, G.
Gunn, G.
Smith, H.
Paton, A.
Paton, J.
Editors
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Journal article
Citation
Journal of Clinical Microbiology, 2003; 41(4):1775-1778
Statement of Responsibility
Claire Jenkins, Neil T. Perry, Tom Cheasty, Darren J. Shaw, Gad Frankel, Gordon Dougan, George J. Gunn, Henry R. Smith, Adrienne W. Paton, and James C. Paton
Conference Name
Abstract
Certain strains of Shiga toxin-producing Escherichia coli (STEC) which do not have the locus of enterocyte effacement pathogenicity island carry the STEC autoagglutinating adhesin (saa) gene. The distribution of the saa gene in STEC isolates from patients with hemolytic-uremic syndrome (HUS), patients with less severe diarrheal disease, asymptomatic individuals, and healthy cattle was examined. saa-positive strains were detected more frequently (P < 0.001) in STEC strains from bovines (32 of 56 strains) than in those from humans (8 of 91 strains). No significant association (P = 0.135) was found between the saa gene and STEC isolated from patients with HUS (6 of 46 strains) or diarrhea (2 of 29 strains) and from healthy controls (0 of 16 strains).