Removal of interferences in the speciation of chromium using an octopole reaction system in ion chromatography with inductively coupled plasma mass spectrometry

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2007

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Chen, Z.
Mallavarapu, M.
Naidu, R.

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Talanta, 2007; 73(5):948-952

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When inductively coupled plasma mass spectrometry (ICP-MS) is used for the detection of <sup>52</sup>Cr (83.8%) species in ion chromatography (IC), interference from polyatomic ions such as <sup>40</sup>Ar<sup>12</sup>C<sup>+</sup> and <sup>35</sup>Cl<sup>16</sup>O<sup>1</sup>H<sup>+</sup>, often occurs due to their mass at m/z 52. To address the issue, an octopole reaction system (ORS) in ICP-MS, including He and H<inf>2</inf> modes, was used to determine whether the background and interference from polyatomic ions could be reduced in the detection of <sup>52</sup>Cr. Compared to standard mode, the polyatomic ions were reduced by either He or H<inf>2</inf>; for example, more than 97 and 98% of <sup>35</sup>Cl was removed using a He and H<inf>2</inf> tune, respectively. However, the detection sensitivity for <sup>52</sup>Cr was decreased, for example, the sensitivity was 27.95 and 67.02% of the standard mode for Cr(EDTA)<inf>2</inf> <sup>-</sup>using a He and H<inf>2</inf> tune, respectively. The H<inf>2</inf> tune is recommended for the detection of <sup>52</sup>Cr at a flow rate of 2.0 mL/min with detection limits in the range of 0.2-0.4 μg/L. The developed method was used to measure chromium speciation in waters containing high concentration of chloride. © 2007 Elsevier B.V. All rights reserved.

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