Fibre-optic photochemical stroke: generating and measuring photochemical changes inside the brain
Date
2014
Authors
Tsiminis, G.
Klarić, T.
Schartner, E.
Warren-Smith, S.
Lewis, M.
Koblar, S.
Monro, T.
Editors
LopezHiguera, J.
Jones, J.
LopezAmo, M.
Santos, J.
Jones, J.
LopezAmo, M.
Santos, J.
Advisors
Journal Title
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Volume Title
Type:
Conference paper
Citation
Proceedings of SPIE, 2014 / LopezHiguera, J., Jones, J., LopezAmo, M., Santos, J. (ed./s), vol.9157, pp.9157D4-1-9157D4-4
Statement of Responsibility
G. Tsiminis, T. S. Klarić, E. P. Schartner, S. C. Warren-Smith, M. D. Lewis, S. A. Koblar, T.
M. Monro
Conference Name
23rd International Conference on Optical Fibre Sensors (2 Jun 2014 - 6 Jun 2014 : Santander, Spain)
Abstract
We report here on the development of a method to induce a stroke in a specific location within a mouse brain through the use of an optical fibre. By capturing the emitted fluorescence signal generated using the same fibre it is then possible to monitor photochemical changes within the brain in real-time, potentially reducing the requirement for post-operative histology to determine if a stroke has successfully been induced within the animal
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© 2014 SPIE