Fibre-optic photochemical stroke: generating and measuring photochemical changes inside the brain

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dc.contributor.authorTsiminis, G.
dc.contributor.authorKlarić, T.
dc.contributor.authorSchartner, E.
dc.contributor.authorWarren-Smith, S.
dc.contributor.authorLewis, M.
dc.contributor.authorKoblar, S.
dc.contributor.authorMonro, T.
dc.contributor.conference23rd International Conference on Optical Fibre Sensors (2 Jun 2014 - 6 Jun 2014 : Santander, Spain)
dc.contributor.editorLopezHiguera, J.
dc.contributor.editorJones, J.
dc.contributor.editorLopezAmo, M.
dc.contributor.editorSantos, J.
dc.date.issued2014
dc.description.abstractWe report here on the development of a method to induce a stroke in a specific location within a mouse brain through the use of an optical fibre. By capturing the emitted fluorescence signal generated using the same fibre it is then possible to monitor photochemical changes within the brain in real-time, potentially reducing the requirement for post-operative histology to determine if a stroke has successfully been induced within the animal
dc.description.statementofresponsibilityG. Tsiminis, T. S. Klarić, E. P. Schartner, S. C. Warren-Smith, M. D. Lewis, S. A. Koblar, T. M. Monro
dc.identifier.citationProceedings of SPIE, 2014 / LopezHiguera, J., Jones, J., LopezAmo, M., Santos, J. (ed./s), vol.9157, pp.9157D4-1-9157D4-4
dc.identifier.doi10.1117/12.2071261
dc.identifier.isbn9781628411751
dc.identifier.issn0277-786X
dc.identifier.issn1996-756X
dc.identifier.orcidTsiminis, G. [0000-0002-4321-3837]
dc.identifier.orcidSchartner, E. [0000-0003-1669-4302]
dc.identifier.orcidWarren-Smith, S. [0000-0002-2612-6344]
dc.identifier.orcidLewis, M. [0000-0002-3332-3776]
dc.identifier.orcidKoblar, S. [0000-0002-8667-203X]
dc.identifier.urihttp://hdl.handle.net/2440/92434
dc.language.isoen
dc.publisherSPIE
dc.relation.granthttp://purl.org/au-research/grants/arc/LP110200736
dc.relation.ispartofseriesProceedings of SPIE
dc.rights© 2014 SPIE
dc.source.urihttps://doi.org/10.1117/12.2071261
dc.subjectOptical fibre sensor; photochemical stroke; in-vivo sensor; fluorescence detection
dc.titleFibre-optic photochemical stroke: generating and measuring photochemical changes inside the brain
dc.typeConference paper
pubs.publication-statusPublished

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