Hypertension: Its prevalence and population-attributable fraction for mortality from cardiovascular disease in the Asia-Pacific region

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dc.contributor.authorMartiniuk, A.
dc.contributor.authorLee, C.
dc.contributor.authorLawes, C.
dc.contributor.authorUeshima, H.
dc.contributor.authorSuh, I.
dc.contributor.authorLam, T.
dc.contributor.authorGu, D.
dc.contributor.authorFeigin, V.
dc.contributor.authorJamrozik, K.
dc.contributor.authorOhkubo, T.
dc.contributor.authorWoodward, M.
dc.date.issued2007
dc.descriptionCopyright © 2007, Lippincott Williams & Wilkins
dc.description.abstractOBJECTIVE: About half of the world's burden of cardiovascular disease is carried by countries in the Asia-Pacific region. This study aimed to quantify the contribution of hypertension to cardiovascular diseases (CVD) at the country level, by calculating the sex-specific, population-attributable fractions (PAFs) for fatal ischaemic heart disease (IHD) and stroke (haemorrhagic and ischaemic) for the World Health Organization Western Pacific and South-east Asian regions. METHODS: The most recent sex-specific prevalence data on hypertension were sought. Age-adjusted hazard ratio (HR) estimates for fatal IHD and stroke associated with hypertension were obtained using Cox analyses of individual participant cohort data from 600,000 adult participants in the Asia-Pacific Cohort Studies Collaboration. HR estimates and prevalence were then used to calculate sex-specific PAFs for fatal IHD and stroke, by country. RESULTS: In 15 countries with available data, the prevalence of hypertension ranged from 5-47% in men and from 7-38% in women. Overall, the fraction of IHD attributable to hypertension ranged from 4-28% in men and from 8-39% in women. Corresponding ranges for haemorrhagic stroke were 18-66% and 15-49%, and for ischaemic stroke were 8-44% and 12-45%. CONCLUSIONS: In the Asia-Pacific region, up to 66% of some subtypes of CVD can be attributed to hypertension, underscoring the immense impact that blood pressure- lowering strategies could have in this populous region.
dc.description.statementofresponsibilityMartiniuk AL, Lee CM, Lawes CM, Ueshima H, Suh I, Lam TH, Gu D, Feigin V, Jamrozik K, Ohkubo T, Woodward M and Asia-Pacific Cohort Studies Collaboration
dc.identifier.citationJournal of Hypertension, 2007; 25(1):73-79
dc.identifier.doi10.1097/HJH.0b013e328010775f
dc.identifier.issn0263-6352
dc.identifier.urihttp://hdl.handle.net/2440/46942
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.source.urihttp://www.jhypertension.com/pt/re/jhypertension/abstract.00004872-200701000-00012.htm
dc.titleHypertension: Its prevalence and population-attributable fraction for mortality from cardiovascular disease in the Asia-Pacific region
dc.typeJournal article
pubs.publication-statusPublished

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