Impact of device length on electrogram sensing in miniaturized insertable cardiac monitors
Date
2022
Authors
Pitman, B.M.
Kadhim, K.
Tarone, R.
Jones, E.
Linz, D.
Lim, M.
Heath, K.M.
Scanlan, N.
Roberts-Thomson, K.C.
Young, G.D.
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Journal article
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Journal of Electrocardiology, 2022; 73:42-48
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Bradley M. Pitman, Kadhim Kadhim, Rachel Tarone, Esther Jones, Dominik Linz, Matthew Lim, Kyle M. Heath, Nicholas Scanlan, Kurt C. Roberts-Thomson, Glenn D. Young, Christopher X. Wong, Prashanthan Sanders, Justin A. Mariani, Dennis H. Lau
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Abstract
Background: Little data exists on electrogram sensing in current generation of miniaturized insertable cardiac monitors (ICMs). Objective: To compare the sensing capability of ICM with different vector length: Medtronic Reveal LINQ (~40 mm) vs. Biotronik Biomonitor III (BM-III, ~70 mm). Methods: De-identified remote monitoring transmissions from n = 40 patients with BM-III were compared with n = 80 gender and body mass index (BMI)-matched patients with Reveal LINQ. Digital measurement of P- and R- wave amplitude from calibrated ICM electrograms was undertaken by 3 investigators independently. Further, we evaluated the impact of BMI and gender on P-wave visibility. Results: Patients in both groups were well matched for gender and BMI (53% male, mean BMI 26.7 kg/m2, both p = NS). Median P- and R-wave amplitude were 97% & 56% larger in the BM-III vs. LINQ [0.065 (IQR 0.039–0.10) vs. 0.033 (IQR 0.022–0.050) mV, p < .0001; & 0.78 (IQR 0.52–1.10) vs. 0.50 (IQR 0.41–0.89) mV, p = .012 respectively). The P/R-wave ratio was 36% greater with the BM-III (p < .001). The 25th percentile of P- wave amplitude for all 120 patients was .026 mV. Logistic regression analysis showed BM-III was more likely than LINQ to have P-wave amplitude ≥.026 mV (OR 7.47, 95%CI 1.965–29.42, p = .003), and increasing BMI was negatively associated with P-wave amplitude ≥.026 mV (OR 0.84, 95%CI 0.75–0.95, p = .004). However, gender was not significantly associated with P-wave amplitude ≥.026 mV (p = .37). Conclusion: The longer ICM sensing vector of BM-III yielded larger overall P- and R- wave amplitude than LINQ. Both longer sensing vector and lower BMI were independently associated with greater P-wave visibility.
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