Control of gene expression in the temperate coliphage 186. X. The cl repressor directly represses transcription of the late control gene B

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dc.contributor.authorDibbens, J.A.
dc.contributor.authorGregory, S.L.
dc.contributor.authorEgan, J.B.
dc.date.issued1992
dc.description.abstractWe have found that the repressor of 186 lytic transcription, CI, represses transcription of the late control gene B, with no involvement of the B protein Itself. In clone studies we showed that CI repressed transcription from the B promoter and that temperature inactivation of CIts led to B derepression. We conclude that CI repressor directly represses transcription of the Bgene and, with prophage induction, it is probable that the inactivation of the CI repressor not only derepresses early lytic transcription, but also derepresses B gene transcription, leading to the activation of transcription from the late promoters.
dc.description.statementofresponsibilityJustin A. Dibbens, Stephen L. Gregory and J. Barry Egan
dc.identifier.citationMolecular Microbiology, 1992; 6(18):2643-2650
dc.identifier.doi10.1111/j.1365-2958.1992.tb01441.x
dc.identifier.issn0950-382X
dc.identifier.issn1365-2958
dc.identifier.orcidGregory, S.L. [0000-0002-0046-5815]
dc.identifier.urihttp://hdl.handle.net/2440/90072
dc.language.isoen
dc.publisherWiley
dc.source.urihttps://doi.org/10.1111/j.1365-2958.1992.tb01441.x
dc.subjectColiphages
dc.subjectTranscription Factors
dc.subjectRepressor Proteins
dc.subjectViral Proteins
dc.subjectVirus Activation
dc.subjectTranscription, Genetic
dc.subjectGene Expression Regulation, Viral
dc.subjectAmino Acid Sequence
dc.subjectBase Sequence
dc.subjectGenes, Viral
dc.subjectMolecular Sequence Data
dc.titleControl of gene expression in the temperate coliphage 186. X. The cl repressor directly represses transcription of the late control gene B
dc.typeJournal article
pubs.publication-statusPublished

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