Sarcopenia measurement in research and clinical practice

dc.contributor.authorDent, E.
dc.contributor.authorWoo, J.
dc.contributor.authorScott, D.
dc.contributor.authorHoogendijk, E.O.
dc.date.issued2021
dc.description.abstractSarcopenia is a disease related to accelerated loss of skeletal muscle and subsequent decline in functional capacity. It affects approximately 13% of the world's population aged over 60 years. Sarcopenia is primarily managed and prevented through a combination of exercise prescription combined with appropriate nutritional strategies. This review outlines diagnostic and case finding/screening tools for age-related (primary) sarcopenia used in research and clinical practice. Diagnostic tools critically reviewed include those of the: European Workgroup for Sarcopenia (EWGSOP) versions 1 and 2; Asian Working Group for Sarcopenia (AWGS) versions 1 and 2; Foundation for the National Institutes of Health (FNIH); and the Sarcopenia Definition and Outcomes Consortium (SDOC). Criteria used by diagnostic tools (muscle mass, muscle strength and physical functioning/performance) are also detailed. Case-finding tools include the SARC-F questionnaire, Ishii's formula and Goodman's screening grid. Additionally, this review discusses the strengths and weaknesses of each diagnostic and case-finding tool, and examines their ability to reliably predict adverse clinical outcomes and patient responses to potential therapies.
dc.description.statementofresponsibilityElsa Dent, Jean Woo, David Scott, Emiel O. Hoogendijk
dc.identifier.citationEuropean Journal of Internal Medicine, 2021; 90:1-9
dc.identifier.doi10.1016/j.ejim.2021.06.003
dc.identifier.issn0953-6205
dc.identifier.issn1879-0828
dc.identifier.orcidDent, E. [0000-0002-4006-3992]
dc.identifier.urihttp://hdl.handle.net/2440/131697
dc.language.isoen
dc.publisherElsevier
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/GNT1112672
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/GNT1123014
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/GNT1174886
dc.rights© 2021 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
dc.source.urihttps://doi.org/10.1016/j.ejim.2021.06.003
dc.subjectAged; 80 and over; sarcopenia; geriatric assessment/methods
dc.titleSarcopenia measurement in research and clinical practice
dc.typeJournal article
pubs.publication-statusPublished

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