The mediterranean diet and cognitive function among healthy older adults in a 6-month randomised controlled trial: the MedLey study

Simple item page
dc.contributor.authorKnight, A.
dc.contributor.authorBryan, J.
dc.contributor.authorWilson, C.
dc.contributor.authorHodgson, J.M.
dc.contributor.authorDavis, C.R.
dc.contributor.authorMurphy, K.J.
dc.date.issued2016
dc.description.abstractEvidence from a limited number of randomised controlled intervention trials (RCTs) have shown that a Mediterranean dietary pattern may reduce the risk of cognitive decline and enhance cognitive function among healthy older adults. However, there are currently no data in non-Mediterranean older adult populations. The present study aimed to address this gap by examining the effect of a Mediterranean dietary pattern (MedDiet) for six months on aspects of cognitive function in a randomised controlled intervention trial (the MedLey study) that extended for a duration of 18 months. In the final analysed cohort, a total of 137 men and women (mean age of 72.1 ± 5.0 years) randomly assigned to either a MedDiet or control diet (HabDiet) (i.e., habitual dietary intake), were assessed on a comprehensive neuropsychological test battery, including 11 individual tests. In multivariable-adjusted models, the MedDiet group did not perform significantly better than the HabDiet control group for executive functioning (adjusted mean differences: +2.53, 95% CI −2.59 to 7.65, p = 0.33); speed of processing (adjusted mean differences: +3.24, 95% CI −1.21 to 7.70, p = 0.15); memory (adjusted mean differences: +2.00, 95% CI −3.88 to 7.88, p = 0.50); visual-spatial ability (adjusted mean differences: +0.21, 95% CI −0.38 to 0.81, 0.48); and overall age-related cognitive performance (adjusted mean differences: +7.99, 95% CI −4.00 to 19.9, p = 0.19). In conclusion, this study did not find evidence of a beneficial effect of a MedDiet intervention on cognitive function among healthy older adults.
dc.description.statementofresponsibilityAlissa Knight, Janet Bryan, Carlene Wilson, Jonathan M. Hodgson, Courtney R. Davis and Karen J. Murphy
dc.identifier.citationNutrients, 2016; 8(9):579-1-579-17
dc.identifier.doi10.3390/nu8090579
dc.identifier.issn2072-6643
dc.identifier.issn2072-6643
dc.identifier.orcidWilson, C. [0000-0002-1883-4690]
dc.identifier.urihttp://hdl.handle.net/2440/104026
dc.language.isoen
dc.publisherMDPI AG
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/1050949
dc.rights© 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
dc.source.urihttps://doi.org/10.3390/nu8090579
dc.subjectMediterranean diet; cognitive function; randomised controlled trial; older adults
dc.titleThe mediterranean diet and cognitive function among healthy older adults in a 6-month randomised controlled trial: the MedLey study
dc.typeJournal article
pubs.publication-statusPublished

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
hdl_104026.pdf
Size:
505.82 KB
Format:
Adobe Portable Document Format
Description:
Published version
Download

Collections

Psychology publications