VEGF receptor signalling in vertebrate development
Date
2010
Authors
Vieira, J.
Ruhrberg, C.
Schwarz, Q.
Editors
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Journal article
Citation
Organogenesis, 2010; 6(2):97-106
Statement of Responsibility
Joaquim Miguel Vieira, Christiana Ruhrberg and Quenten Schwarz
Conference Name
Abstract
The secreted glycoprotein vascular endothelial growth factor A (VEGF or VEGFA) affects many different cell types and modifies a wide spectrum of cellular behaviors in tissue culture models, including proliferation, migration, differentiation and survival. The versatility of VEGF signaling is reflected in the complex composition of its cell surface receptors and their ability to activate a variety of different downstream signaling molecules. A major challenge for VEGF research is to determine which of the specific signaling pathways identified in vitro control development and homeostasis of tissues containing VEGF-responsive cell types in vivo.
School/Discipline
Dissertation Note
Provenance
Description
Link to a related website: http://europepmc.org/articles/pmc2901813?pdf=render, Open Access via Unpaywall
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Copyright © 2010 Landes Bioscience